55483-70-0

Basic information

• Product Name: 4-AMino-2-ethoxyphenol
• Synonyms: 4-AMino-2-ethoxyphenol;4-Amino-2-ethoxypheno
• CAS NO: 55483-70-0
• Molecular Formula: C₈H₁₁NO₂
• Molecular Weight: 153.17844
• Mol File: 55483-70-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 186-188 °C
• Boiling Point: 316.7±27.0 °C(Predicted)
• Appearance: /
• Density: 1.172±0.06 g/cm3(Predicted)
• PKA: 10.36±0.18(Predicted)
• CAS DataBase Reference: 4-AMino-2-ethoxyphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMino-2-ethoxyphenol(55483-70-0)
• EPA Substance Registry System: 4-AMino-2-ethoxyphenol(55483-70-0)

Safety Data

• Hazardous Substances Data: 55483-70-0(Hazardous Substances Data)

Upstream product

• 88331-63-9 2-ethoxy-4-nitroso-phenol 
• 94-71-3 2-Ethoxyphenol 
• 4992-63-6 4-Nitro-1,2-diethoxybenzene 
• 3316-09-4 1,2-dihydroxy-4-nitrobenzene 
• 40130-25-4 3-ethoxy-4-hydroxynitrobenzene 
• 91861-93-7 N-(m-Ethoxyphenyl)hydroxylamine 

Downstream Products

• 135325-75-6 N-(3-ethoxy-4-hydroxyphenyl)acetamide 
• 26692-07-9 2-[(4-decyloxy-3-ethoxy-phenylamino)-methylene]-malonic acid diethyl ester 
• 18507-89-6 decoquinate 
• 55483-71-1 3-Ethoxy-4-hydroxy-anilinomethylenmalonsaeurediethylester 
• 84702-04-5 3,4-diethoxyacetanilide 
• 861796-51-2 3-ethoxy-4-methoxyacetanilide 
• 477742-46-4 3-ethoxy-4-methoxy-aniline 
• 39052-12-5 3,4-diethoxyaniline 
• 601488-03-3 2-acetoxy-3-(3-ethoxy-2-hydroxy-5-isopropoxycarbonylamino-phenylsulfanyl)-propionic acid ethyl ester 
• 135325-73-4 isopropyl 3-ethoxy-4-hydroxycarbanilate 

Relevant articles and documents

Synthetic method of decoquinate

The invention discloses a synthetic method of decoquinate, and belongs to the technical field of pharmaceutical engineering. The synthetic method takes o-hydroxyphenyl ethyl ether as a raw material to prepare decoquinate via the processes of coupling, reduction, condensation, etherification, cyclization and the like. The process of reduction in the method adopts environment-friendly hydrazine hydrate as a reducer to reduce an azo-compound and introduce an amino group, so that the synthetic method is good in selectivity, and environmentally friendly, and beneficial for reducing environmental pollution problems; BTC is adopted as a cyclization reagent in the process of cyclization, so that the condition is mild, the requirement on equipment is lowered, and the cost is reduced.

Synthesis and anticoccidial activities of Quinoline Carboxylate derivatives with Methyl (E)-2-(3-methoxy)acrylate moiety

A series of novel quinoline carboxylate derivatives with methyl (E)-2-(3-methoxy) acrylate group were designed and synthesized as anticoccidial medicines. The structures were confirmed by 1H NMR, IR and HR-MS spectra. The biological activities were primarily evaluated according to the anticoccidial index method. The results indicated that these compounds (7c, 7d, 7e, 7g) exhibited anticoccidial activities against Eimeria tenella. In particular, the anticoccidial index of 6-decyloxy-7-ethoxy-4-{6-[2-(2-methoxy-1-methoxycarbonyl- vinyl)phenoxy]pyrimidin-4-yloxy}- quinoline-3-carboxylic acid ethyl ester (7e) was 168.7, which indicated that the compound has a good anticoccidial activity.

Synthesis and anticoccidial activity of ethyl 6-substitutedbenzyloxy-7- alkoxy-4-hydroxyquinoline-3-carboxylates

A series of novel ethyl 6-substitutedbenzyloxy-7-alkoxy-4-hydroxyquinoline- 3-carboxylates have been designed and synthesised from 4-nitro-2-alkoxyphenol. Their structures have been characterised by 1H NMR, HRMS and IR spectra. Anticoccidial activities of