5573-42-2

Basic information

• Product Name: Diphenylphosphinic acid benzyl ester
• Synonyms: Diphenylphosphinic acid benzyl ester
• CAS NO: 5573-42-2
• Molecular Formula: C₁₉H₁₇O₂P
• Molecular Weight: 308.3108
• Mol File: 5573-42-2.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 445.7°Cat760mmHg
• Flash Point: 236.7°C
• Appearance: /
• Density: 1.19g/cm³
• Vapor Pressure: 1.01E-07mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: Diphenylphosphinic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Diphenylphosphinic acid benzyl ester(5573-42-2)
• EPA Substance Registry System: Diphenylphosphinic acid benzyl ester(5573-42-2)

Safety Data

• Hazardous Substances Data: 5573-42-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C19H17O2P/c20-22(18-12-6-2-7-13-18,19-14-8-3-9-15-19)21-16-17-10-4-1-5-11-17/h1-15H,16H2

Upstream product

• 1707-03-5 diphenyl-phosphinic acid 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 108-88-3 toluene 
• 4559-70-0 Diphenylphosphine oxide 
• 100-51-6 benzyl alcohol 
• 1079-66-9 chloro-diphenylphosphine 
• 2959-74-2 benzyldiphenylphosphine oxide 
• 1499-21-4 Diphenylphosphinic chloride 
• 127207-99-2 Benzyl N-benzylidene-α-(diphenylphosphinoyl)glycinate 
• 107-13-1 acrylonitrile 
• 103-26-4 Methyl cinnamate 
• 17223-05-1 diphenylphosphinic acid potassium salt 
• 53772-44-4 benzyloxydiphenylphosphine 

Downstream Products

• 27127-09-9 N,N-dibenzyl-P,P-diphenylphosphinic amide 
• 59579-03-2 1-Methylbutyldiphenylphosphinoxid 
• 27127-08-8 N-benzyl-P,P-diphenylphosphinic amide 
• 54894-37-0 (2-(benzyloxy)ethyl)benzene 
• 101430-90-4 [2-(benzyloxy)propyl]benzene 
• 103-50-4 dibenzyl ether 
• 16224-09-2 benzyl cyclohexyl ether 

Relevant articles and documents

Bu4NI-Catalyzed Dehydrogenative Coupling of Diaryl Phosphinic Acids with C(sp3)-H Bonds of Arenes

An efficient phosphorylation of C(sp3)-H bonds of arenes with diaryl phosphinic acids via Bu4NI-catalyzed dehydrogenative coupling has been developed. This transformation proceeds efficiently under transition-metal-free reaction conditions and represents a straightforward method to prepare valuable organophosphorus compounds from readily available arenes and diaryl phosphinic acids.

Tf2O/DMSO-Promoted P-O and P-S Bond Formation: A Scalable Synthesis of Multifarious Organophosphinates and Thiophosphates

A Tf2O/DMSO-based system for the dehydrogenative coupling of a wide range of alcohols, phenols, thiols, and thiophenols with diverse phosphorus reagents has been developed. This metal- and strong-oxidant-free strategy provides a facile approach to a great variety of organophosphinates and thiophosphates. The simple reaction system, good functional-group tolerance, and broad substrate scope enable the application of this method to the modification of natural products and the direct synthesis of bioactive molecules and flame retardants.

Novel method for preparing phosphonate through oxidative dehydrogenation coupled reaction of copper-catalyzed diarylphosphine oxide and alcohol

The invention provides a method for efficiently and highly selectively synthesizing phosphonate derivatives containing different substituted functional groups. According to the method, cuprous iodideis used as a catalyst, 2,2'-dipyridyl is used as a ligand, pyridine is used as an alkali, oxygen is used as an oxidant, diarylphosphine oxide and an alcohol compound are used as reaction substrates, and an organic solvent is added into a reaction system. The method has the advantages that the catalyst and the oxidant are cheap and easily available; substrate applicability is high; reaction conditions are mild, safe and reliable; the selectivity of the obtained target products is close to 100%; and the yield of the target products is as high as 90% or above. The method overcomes the defects ofpoor reaction selectivity, complex reaction steps, low yield, need for reagents harmful to the environment and the like in the traditional synthesis of phosphonate derivatives, and has favorable industrial application prospects. The invention also provides the corresponding phosphonate derivatives containing different substituted functional groups.