5618-03-1

Usage

Uses

Used in Pharmaceutical Industry:
3-Cyclopropylpropionic acid is used as a chemical intermediate for the synthesis of various pharmaceuticals, leveraging its unique stereochemistry to enhance the efficacy and selectivity of drug molecules.
Used in Agrochemical Production:
In the agrochemical industry, 3-Cyclopropylpropionic acid is utilized as a building block in the development of new agrochemicals, contributing to the creation of more effective and targeted pest control solutions.
Used in Specialty Chemicals:
3-Cyclopropylpropionic acid is employed as a key component in the production of specialty chemicals, where its unique structural properties are harnessed to create high-performance materials for specific applications.

InChI:InChI=1/C6H10O2/c7-6(8)4-3-5-1-2-5/h5H,1-4H2,(H,7,8)

Upstream product

• 186581-53-3 diazomethane 
• 54322-65-5 cyclopropylacetyl chloride 
• 36982-56-6 (2-bromoethyl)cyclopropane 
• 124-38-9 carbon dioxide 
• 5239-82-7 cyclopropylacetic acid 
• 62021-36-7 3-cyclopropyl propionic acid ethyl ester 
• 64-19-7 acetic acid 
• 7051-34-5 cyclopropylcarbinyl bromide 
• 21014-26-6 ethyl 3-cyclopropaneprop-2-enoate 
• 34108-21-9 methyl cyclopropylacetate 
• 14902-14-8 -triphenyl-phosphoran 
• 2566-44-1 1-cyclopropylethanol 

Downstream Products

• 56105-20-5 cyclopropylpropionyl chloride 
• 1375087-25-4 N-[3-(4-chloro-3-methylphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl]-3-cyclopropylpropanamide 
• 289677-11-8 (R)-4-benzyl-3-(3-cyclopropylpropanoyl)oxazolidin-2-one 

Relevant academic research and scientific papers

Synthesis and pharmacological in vitro investigations of novel shikonin derivatives with a special focus on cyclopropane bearing derivatives

Melanoma is the deadliest form of skin cancer and accounts for about three quarters of all skin cancer deaths. Especially at an advanced stage, its treatment is challenging, and survival rates are very low. In previous studies, we showed that the constitu

Preparation method of cyclopropylpropionic acid

The invention relates to a synthetic method of cyclopropylpropionic acid. Technical problems of synthesis operation difficulty and expensive raw material are solved. A conventional industrial raw material cyclopropanecarboxaldehyde is used as a starting raw material and triethyl phosphonoacetate undergo a Wittig reaction to obtain 3-cyclopropyl-ethyl acrylate; 3-cyclopropyl-ethyl acrylate and sodium borohydride undergo reduction of double bonds in the presence of Lewis acid to obtain 3-cyclopropyl-ethyl propionate; and 3-cyclopropyl-ethyl propionate is hydrolyzed under an alkaline condition so as to obtain cyclopropylpropionic acid. A chemical equation is as shown in the specification.

Potassium Channel Modulators

Disclosed herein are KCNQ potassium channels modulators of formula (I) wherein R1, R2, R3, R4, and R5 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.

Cyclopentyl modulators of chemokine receptor activity

The present invention is directed to compounds of the formula I: (wherein R1, R2, R3, R4, R5, R7, R8, X, n, x and y are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.

TRIAZOLO-1,4-DIAZEPINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS

A triazolo-1,4-di-azepine compound of the below given formulas and a pharmacologically acceptable salt thereof are disclosed and useful in the pharmaceutical field, especially to allergic diseases. STR1 in which R1 and R2 are hydrogen or an alkyl, R3 is hydrogen or a halogen, R4 is hydrogen or an alkyl, X is--OCO--,--NHCO--,--CO--or others and Y is a cycloalkyl, a cycloalkylalkyl, an alkynyl or others.