5651-47-8

Usage

Uses

Used in Pharmaceutical Industry:
NISTC5651478 is used as a pharmaceutical intermediate for the synthesis of various pharmaceuticals and organic chemicals. Its antiseptic and analgesic properties make it a valuable component in the development of new medications.
Used in Cosmetics Industry:
NISTC5651478 is used as an ingredient in topical ointments and medicated creams due to its antiseptic and analgesic properties, contributing to the treatment and relief of skin conditions.
Used in Dye and Perfume Production:
NISTC5651478 is used as a key component in the production of dyes and perfumes, leveraging its chemical properties to create a variety of colorants and fragrances.
Used in Food and Beverage Industry:
NISTC5651478 is used as a preservative and flavor enhancer in the food and beverage industry, ensuring the freshness and taste of products while extending their shelf life.

InChI:InChI=1/C10H12O2/c1-7(2)8-4-3-5-9(6-8)10(11)12/h3-7H,1-2H3,(H,11,12)

Upstream product

• 5433-01-2 1-bromo-3-isopropylbenzene 
• 124-38-9 carbon dioxide 
• 51688-76-7 4-amino-3-isopropylbenzoic acid 
• 98-82-8 Isopropylbenzene 
• 51605-97-1 2-bromo-4-isopropylaniline 
• 99-88-7 4-Isopropylaniline 
• 30951-66-7 2-(3-bromophenyl)-2-propanol 
• 64-18-6 formic acid 
• 61843-02-5 3-isopropyl benzamide 
• 108-20-3 di-isopropyl ether 
• 65-85-0 benzoic acid 
• 40751-59-5 3-isopropyl benzonitrile 
• 1822-71-5 n-pentylsodium 
• 4522-40-1 ethyl potassium 

Downstream Products

• 325770-58-9 3-isopropylbenzoyl chloride 
• 51473-70-2 1-(m-isopropylphenyl)methanol 
• 457928-84-6 (S)-3-(3-isopropylphenyl)butanal 
• 1361926-29-5 ethyl 4-methyl-2-oxo-4-(m-isopropylphenyl)but-3-enoate 
• 34246-57-6 3-isopropylbenzaldehyde 
• 1616670-18-8 5-[5-(3-isopropyl-benzoylamino)-2-methyl-benzylamino]-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester 
• 1449590-11-7 (E)-(1-(4-isopropylphenyl)ethene-1,2-diyl)dibenzene 
• 61843-02-5 3-isopropyl benzamide 
• 40751-59-5 3-isopropyl benzonitrile 
• 1443755-90-5 [1-(3-chloro-phenyl)-1H-[1,2,4]triazol-3-yl]-[4-(3-isopropyl-benzoyl)-2,2-dimethyl-piperazin-1-yl]-methanone 
• 1443756-74-8 [4-(3-isopropyl-benzoyl)-2,2-dimethyl-piperazin-1-yl]-(1-phenyl-1H-[1,2,4]triazol-3-yl)-methanone 
• 40428-87-3 1-[3-(propan-2-yl)phenyl]ethan-1-one 
• 1429312-27-5 3-isopropyl-N-methoxy-N-methylbenzamide 
• 32388-78-6 N-(m-Isopropylbenzhydryl)-anilin 

Relevant academic research and scientific papers

Flow hydrodediazoniation of aromatic heterocycles

Continuous flow processing was applied for the rapid replacement of an aromatic amino group with a hydride. The approach was applied to a range of aromatic heterocycles, confirming the wide scope and substituent-tolerance of the processes. Flow equipment was utilized and the process optimised to overcome the problematically-unstable intermediates that have restricted yields in previous studies relying on batch procedures. Various common organic solvents were investigated as potential hydride sources. The approach has allowed key structures, such as amino-pyrazoles and aminopyridines, to be deaminated in good yield using a purely organic-soluble system.

Inclusion complex containing epoxy resin composition for semiconductor encapsulation

The invention is an epoxy resin composition for sealing a semiconductor, including (A) an epoxy resin and (B) a clathrate complex. The clathrate complex is one of (b1) an aromatic carboxylic acid compound, and (b2) at least one imidazole compound represented by formula (II): wherein R2 represents a hydrogen atom, C1-C10 alkyl group, phenyl group, benzyl group or cyanoethyl group, and R3 to R5 represent a hydrogen atom, nitro group, halogen atom, C1-C20 alkyl group, phenyl group, benzyl group, hydroxymethyl group or C1-C20 acyl group. The composition has improved storage stability, retains flowability when sealing, and achieves an effective curing rate applicable for sealing delicate semiconductors.

Direct carboxylation of simple arenes with CO2 through a rhodium-catalyzed C-H bond activation

Direct carboxylation of simple arenes under atmospheric pressure of CO2 is achieved through a rhodium-catalyzed C-H bond activation without the assistance of a directing group. Various arenes such as benzene, toluene, xylene, electron-rich or electron-deficient benzene derivatives, and heteroaromatics are directly carboxylated with high TONs. This journal is

Enantioselective copper-catalyzed conjugate addition of trimethylaluminium to β,γ-unsaturated α-ketoesters

Not a cop out: The copper-catalyzed asymmetric conjugate addition of organometallic reagents to Michael acceptors is an important methodology for forming a C-C bond in an enantioselective manner. Such an addition of Me 3Al to β,γ-unsaturated α-

ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES

The present invention relates to anilinopyrazole compounds of formula (1) in which R3 represents an aromatic 5- or 6-membered heteroaromatic ring which is optionally fused to phenyl, said heterocycle or fused heterocycle is optionally substituted, X represents a carboxylic acid, ester or amide, or sulfonamide, and the remaining groups are as defined in the text. It also relates to pharmaceutical compositions containing these materials and, and methods for treating diabetes and related disorders using these materials.

CHEMICAL COMPOUNDS

The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.

HETEROCYCLIC CYTOKINE INHIBITORS

The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory, anti-pain or anti-cancer agents. There are further provided m

QUINOXALINES AS B RAF INHIBITORS

The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.

Substituted 1,3-thiazole compounds, their production and use

(1) A 1,3-thiazole compound of which the 5-position is substituted with a 4-pyridyl group having a substituent including no aromatic group or (2) a 1,3-thiazole compound of which the 5-position is substituted with a pyridyl group having at the position adjacent to a nitrogen atom of the pyridyl group a substituent including no aromatic group has an excellent p38 MAP kinase inhibitory activity.

Palladium(II)-catalyzed sequential hydroxylation-carboxylation of biphenyl using formic acid as a carbonyl source

(Equation Presented) A simultaneous hydroxylation-carboxylation of biphenyl occurred to give 4′-hydroxy-4-biphenylcarboxylic acid, which has wide potential application as a polyester monomer.