5692-19-3

Upstream product

• 124-42-5 acetamidine hydrochloride 
• 98-88-4 benzoyl chloride 
• 65-85-0 benzoic acid 
• 55-21-0 benzamide 
• 75-05-8 acetonitrile 
• 93-99-2 benzoic acid phenyl ester 
• 1199-00-4 3-methyl-5-phenyl-[1,2,4]oxadiazole 

Downstream Products

• 1199-00-4 3-methyl-5-phenyl-[1,2,4]oxadiazole 
• 1465766-60-2 1-mesityl-3-methyl-5-phenyl-1H-[1,2,4]-triazole 
• 1465766-35-1 C₄₅H₅₄IrN₉ 
• 1465766-45-3 C₆₀H₇₂Cl₂Ir₂N₁₂ 
• 1465766-41-9 C₅₄H₅₄IrN₉ 
• 1465766-43-1 1-cyclohexyl-3-methyl-5-phenyl-1H-1,2,4-triazole 
• 1575-95-7 N-acetylbenzamide 

Relevant academic research and scientific papers

A metal-free tandem approach to prepare structurally diverse N-heterocycles: Synthesis of 1,2,4-oxadiazoles and pyrimidinones

A metal-free one-pot approach to the diversity oriented synthesis of N-heterocycles, 1,2,4-oxadiazoles and 2,6 disubstituted pyrimidin-4-ones is described via carboxamidation of amidines with aryl carboxylic acids and aryl propargylic acids. The reactions occur at room temperature forming N-acylamidines which undergo tandem nucleophilic addition-deamination- intramolecular cyclisation to give the corresponding heterocyclic compounds in good to excellent yields. This one pot approach has led to the successful synthesis of the drug lead molecule, ataluren, 3-(5-(2-fluorophenyl)-1,2,4- oxadiazol-3-yl) benzoic acid in two steps. the Partner Organisations 2014.

BLUE LUMINESCENT COMPOUNDS

There is provided a compound having Formula (I). In the formula: R1 can be alkyl, aryl, alkylaryl, or deuterated analogs thereof; R2 can be alkyl or deuterated alkyl; R3 can be H, D, aryl, or deuterated aryl; and R4-R6 are the same or different and can be H, D, alkyl, or deuterated alkyl. In the formula, at least one of the following conditions is met: (i) R1 is a secondary alkyl, a tertiary alkyl, aryl, alkylaryl, or deuterated analog thereof; (ii) R3 is aryl or deuterated aryl; (iii) at least one of R3-R6 is D.

Acylation of Dibasic Compounds Containing Amino Amidine and Aminoguanidine Functions

The site of acylation in difunctional compounds containing an amine and either an amidine or guanidine can be determined from the ultraviolet absorption spectrum of the acylated product.If the amidine or guanidine has been acylated, the product possesses a chromophore that is pH dependent, whereas if an amide was formed, the chromophore is independent of pH.