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8-CHLORO-2H-1,4-BENZOXAZIN-3(4H)-ONE is a synthetic organic compound with the chemical formula C8H4ClNO2. It belongs to the class of benzoxazinones and is characterized by the presence of a chlorine atom and a benzoxazinone ring structure. 8-CHLORO-2H-1,4-BENZOXAZIN-3(4H)-ONE serves as a valuable building block for the creation of novel chemical compounds with potential biological activity.

57245-31-5

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57245-31-5 Usage

Uses

Used in Pharmaceutical Industry:
8-CHLORO-2H-1,4-BENZOXAZIN-3(4H)-ONE is used as an intermediate in the synthesis of various drugs and pharmaceutical products. Its unique structure and properties make it a promising candidate for the development of new therapeutic agents.
Used in Research and Development:
8-CHLORO-2H-1,4-BENZOXAZIN-3(4H)-ONE is utilized in research and development for the exploration of its potential biological activity and applications in the creation of novel chemical compounds. Its precise uses may vary depending on the specific research or manufacturing needs.

Check Digit Verification of cas no

The CAS Registry Mumber 57245-31-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,2,4 and 5 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 57245-31:
(7*5)+(6*7)+(5*2)+(4*4)+(3*5)+(2*3)+(1*1)=125
125 % 10 = 5
So 57245-31-5 is a valid CAS Registry Number.

57245-31-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-chloro-4H-1,4-benzoxazin-3-one

1.2 Other means of identification

Product number -
Other names 8-chloro-3,4-dihydro-2H-1,4-benzoxazin-3-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57245-31-5 SDS

57245-31-5Relevant academic research and scientific papers

Discovery of a lead series of potent benzodiazepine 5-HT2C receptor agonists with high selectivity in functional and binding assays

Dang, Huong,Feichtinger, Konrad,Frazer, John,Grottick, Andrew J.,Kasem, Michelle,Le, Minh,Lehman, Juerg,Morgan, Michael E.,Ren, Albert,Sage, Carleton R.,Schrader, Thomas O.,Semple, Graeme,Unett, David J.,Whelan, Kevin T.,Wong, Amy,Zhu, Xiuwen

supporting information, (2020/01/22)

A series of potential new 5-HT2 receptor scaffolds based on a simplification of the clinically studied, 5-HT2CR agonist vabicaserin, were designed. An in vivo feeding assay early in our screening process played an instrumental part in the lead identification process, leading us to focus on a 6,5,7-tricyclic scaffold. A subsequent early SAR investigation provided potent agonists of the 5-HT2C receptor that were highly selective in both functional and binding assays, had good rat PK properties and that significantly reduced acute food intake in the rat.

Microwave-assisted synthesis of benzo-[1,4]-oxazinones using MeO-PEG-OMe as solvent

Lim, Jae-Min,Gam, Gyunghee,Kim, Shin-Hyuong,Shin, Dong-Soo,Jang, Kiwan

, p. 468 - 472,5 (2020/08/31)

Efficient one-pot microwave-assisted synthesis of various benzo-[1,4]-oxazinones via Smiles rearrangement is described. Treatment of 2-chloroacetamide, substituted 2-chlorophenols and cesium carbonate in MeO-PEG-OMe (2,000) as solvent afforded the corresp

Morpholine derivatives

-

, (2008/06/13)

The disclosure relates to new morpholine derivatives which possess antidepressant activity, to processes for the manufacture of said derivatives and to pharmaceutical compositions containing them. Typical of the morpholine derivatives disclosed is 2-(4H-2

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