578020-90-3

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 578020-89-0 methyl [5-(dimethoxymethyl)-2,3-dimethoxyphenyl]acetate 
• 5653-67-8 2,3-dimethoxybenzyl alcohol 
• 22280-95-1 4-allyloxy-3-methoxybenzaldehyde 
• 121-33-5 vanillin 
• 578020-88-9 (5-formyl-2,3-dimethoxyphenyl)acetic acid 
• 578020-87-8 (5-dimethoxymethyl)-1,2-dimethoxy-3-(prop-2-enyl)benzene 
• 578020-86-7 methyl (5-formyl-2,3-dimethoxyphenyl)acetate 
• 86-51-1 2,3-dimethyoxybenzaldehyde 
• 3893-01-4 2,3-dimethoxybenzyl chloride 
• 67483-49-2 3,4-dimethoxy-5-(prop-2-enyl)benzaldehyde 
• 27466-90-6 methyl (2,3-dimethoxyphenyl)acetate 
• 90-53-9 2,3-dimethoxyphenylacetic acid 
• 4468-57-9 2-(2,3-dimethoxyphenyl)acetonitrile 

Relevant academic research and scientific papers

An improved and versatile method for the rapid synthesis of aryldihydrobenzofuran systems by a boron tribromide-mediated cyclization reaction

Boron tribromide is presented as a highly reactive reagent that simultaneously allows the demethylation and fully diastereoselective cyclization of different precursor molecules, obtained by an aldol-type reaction, to a series of hydroxylated aryldihydrobenzofuran systems in racemic form. The latter are often found as key structures in natural compounds of different classes. Syntheses of educts, which mainly took advantage of a versatile Rieche formylation, are also described.