59106-34-2Relevant articles and documents
Stereoselective Halo-Succinimide Facilitated α-Halogenations of Substituted α-Trialkylsilyl-β-Substituted-α,β-Unsaturated Esters
Jennings, Michael P.,Probasco, Kristina C.
, p. 8945 - 8954 (2021/07/20)
The NXS (X = Cl, Br)-mediated halogenation of a series of (E)-α-trimethylsilyl-β-alkyl(aryl)-α,β-unsaturated esters in dimethylformamide (DMF) has furnished (Z)-β-substituted-α-halogenated-α,β-unsaturated ester products in moderate to high isolated yields (58-90%) with dr values of >20:1 coupled with the inversion of olefin stereochemistry. The reaction process was hypothesized to include an initial halonium cation intermediate, followed by regioselective ring opening with DMF. Subsequentanti-E2-type concomitant elimination allowed for the stereoselective formation of the product vinylic bromo-and chloroesters.
A process for synthesizing substituted α α -, β - unsaturated carboxylic acid ester compound and its preparation and application method
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Paragraph 0040-0043, (2017/08/25)
The invention belongs to the technical field of organic synthesis, and particularly relates to an alpha-diphenylphosphinesubstituted alpha, beta-unsaturated carboxylatecompound as well as preparation and application methods. A simple reagent phosphorus ylide and aromatic aldehyde are taken as raw materials, a Wittig reactionand a phosphorus ylidereaction of carboxylate ester are performed, a halogenating agent is added, halogenated alpha, beta-unsaturated carboxylate ester is generated and reacts with diphenylphosphine under catalysis of a palladium reagent, and a target product with high yield is generated. Carboxylate of the compound can be transformed into other groups, so that a novel organicphosphine catalyst is generated.
Synthesis, characterization, and catalytic activity of ionic liquids based on biosources
Moriel,García-Suárez,Martínez,García,Montes-Morán,Calvino-Casilda,Ba?ares
supporting information; experimental part, p. 4877 - 4881 (2010/10/02)
New room-temperature ionic liquids were synthesized from natural and easily available feedstocks (choline hydroxide and amino acids) following an economical and green route in which the only by-product was water. They were successfully applied as catalyst
