59852-82-3

Basic information

• Product Name: 1-(4-BENZYLAMINO-PHENYL)-ETHANONE
• Synonyms: 1-(4-BENZYLAMINO-PHENYL)-ETHANONE
• CAS NO: 59852-82-3
• Molecular Formula: C₁₅H₁₅NO
• Molecular Weight: 225.2857
• Mol File: 59852-82-3.mol
• Article Data: 56

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-BENZYLAMINO-PHENYL)-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-BENZYLAMINO-PHENYL)-ETHANONE(59852-82-3)
• EPA Substance Registry System: 1-(4-BENZYLAMINO-PHENYL)-ETHANONE(59852-82-3)

Safety Data

• Hazardous Substances Data: 59852-82-3(Hazardous Substances Data)

Usage

General Description

1-(4-benzylamino-phenyl)-ethanone is a chemical compound with the molecular formula C15H15NO. It is a ketone with a benzene ring and an amino group attached to the phenyl group. 1-(4-BENZYLAMINO-PHENYL)-ETHANONE is used in organic synthesis and medicinal chemistry as a building block for more complex molecules. It can also be used as a reagent in various chemical reactions due to its unique structure, making it a versatile compound in the field of chemical research and development. Additionally, it has potential applications in pharmaceuticals, agrochemicals, and materials science due to its versatile and reactive nature.

Upstream product

• 13329-40-3 4-Iodoacetophenone 
• 100-46-9 benzylamine 
• 100-19-6 (4-nitrophenyl)ethanone 
• 100-51-6 benzyl alcohol 
• 100-52-7 benzaldehyde 
• 538-51-2 benzylidene phenylamine 
• 99-92-3 p-aminobenzophenone 
• 108-88-3 toluene 
• 100-39-0 benzyl bromide 
• 622-30-0 N-benzyl hydroxylalmine 
• 149104-90-5 4-acetylphenylboronic acid 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 403-41-8 1-(4-Fluorophenyl)ethanol 
• 99-91-2 para-chloroacetophenone 

Relevant articles and documents

Porous polymeric ligand promoted copper-catalyzed C-N coupling of (hetero)aryl chlorides under visible-light irradiation

A porous polymeric ligand (PPL) has been synthesized and complexed with copper to generate a heterogeneous catalyst (Cu@PPL) that has facilitated the efficient C-N coupling with various (hetero)aryl chlorides under mild conditions of visible-light irradiation at 80 °C (58 examples, up to 99% yields). This method could be applied to both aqueous ammonia and substituted amines, and is compatible to a variety of functional groups and heterocycles, as well as allows tandem C-N couplings with conjunctive dihalides. Furthermore, the heterogeneous characteristic of Cu@PPL has enabled a straightforward catalyst separation in multiple times of recycling with negligible catalytic efficiency loss by simple filtration, affording reaction mixtures containing less than 1 ppm of Cu residue. [Figure not available: see fulltext.]

Iron-Catalyzed Oxidative Amination of Benzylic C(sp3)–H Bonds with Anilines

Iron-catalyzed oxidative amination of benzylic C(sp3)–H bonds with anilines bearing electron-withdrawing groups (EWGs) or electron-donating groups (EDGs) is realized based on simple variations of N-substituents on imidazolium cations in novel ionic Fe(III) complexes. The structural modification of the imidazolium cation resulted in regulation of the redox potential and the catalytic performance of the iron metal center. Using DTBP as oxidant, [HItBu][FeBr4] showed the highest catalytic activity for anilines bearing EWGs, while [HIPym][FeBr4] was more efficient for EDG-substituted anilines. This work provides alternative access to benzylamines with the advantages of both a wide substrate scope and iron catalysis.

Thioglycerol-Stabilized Rhodium Nanoparticles in Biphasic Medium as Catalysts in Multistep Reactions

Small rhodium nanoparticles (ca. 3.5 nm) were prepared by the decomposition of an organometallic precursor under hydrogen pressure in glycerol using 1-thioglycerol as stabilizer. Full characterization in the solid state [HR-TEM, EDX, XPS] showed a fcc structure for the Rh0/RhI nanoparticles capped with thiolate ligand. Reduction of different functionalities, including nitro groups and imines, was applied to tandem reductive amination of aldehydes with primary and secondary amines, and to the synthesis of N-substituted anilines from nitrobenzene. In addition, thiolate-capped RhNPs could be recovered and reused up to 5 runs without loss of activity nor selectivity.