60407-53-6 Usage
Uses
Used in Scientific Research:
alpha-(Aminomethyl)-2,5-dimethoxybenzenemethanol hydrochloride is used as a research tool for investigating the role of the 5-HT2A receptor in the brain. It aids in understanding the receptor's function and its involvement in various neurological processes.
Used in Pharmaceutical Applications:
In the pharmaceutical industry, alpha-(Aminomethyl)-2,5-dimethoxybenzenemethanol hydrochloride is used as a selective agonist to explore its potential therapeutic effects in the treatment of psychiatric disorders. Its interaction with the 5-HT2A receptor makes it a candidate for developing new treatments for such conditions.
Used in Central Nervous System Studies:
alpha-(Aminomethyl)-2,5-dimethoxybenzenemethanol hydrochloride is utilized as a chemical probe in studies related to the central nervous system. It helps researchers to examine the receptor's activity and its impact on neurotransmitter levels, which is crucial for understanding the underlying mechanisms of various neurological and psychiatric disorders.
Used in Behavioral Pharmacology:
As a selective agonist for the 5-HT2A receptor, alpha-(Aminomethyl)-2,5-dimethoxybenzenemethanol hydrochloride is used in behavioral pharmacology to study the effects of this receptor on behavior. This can provide insights into the development of drugs that target specific behaviors associated with mental health conditions.
Used in Neurotransmitter Modulation Research:
alpha-(Aminomethyl)-2,5-dimethoxybenzenemethanol hydrochloride is employed in research aimed at modulating neurotransmitter levels and receptor activity in the brain. Its ability to selectively activate the 5-HT2A receptor makes it a valuable compound for investigating the intricate balance of neurotransmitters and their influence on brain function and behavior.
Check Digit Verification of cas no
The CAS Registry Mumber 60407-53-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,4,0 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 60407-53:
(7*6)+(6*0)+(5*4)+(4*0)+(3*7)+(2*5)+(1*3)=96
96 % 10 = 6
So 60407-53-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H15NO3.ClH/c1-13-7-3-4-10(14-2)8(5-7)9(12)6-11;/h3-5,9,12H,6,11H2,1-2H3;1H
60407-53-6Relevant articles and documents
Asymmetric synthesis of both enantiomers of 2-(dimethylamino)-1-[3-methoxy-2-(1-methyletyhoxy)phenyl]ethanol
Philippo,Fett,Bovy,Barras,Angel,Georges,Ochsenbein
, p. 881 - 888 (2007/10/03)
Both enantiomers of 2-(dimethylamino)-1-[3- methoxy-2-(1-methylethoxy)phenyl]ethanol were synthetized by a stereoselective route and evaluated in vitro for their uroselectivity in comparison with other α1-adrenoceptor agonists. The most potent enantiomer was structurally characterized by X-ray crystallographic analysis.
Conformational Effects on the Activity of Drugs. 10. Synthesis, Conformation, and Pharmacological Properties of 1-(2,5-Dimethoxyphenyl)-2-aminoethanols and Their Morpholine Analogues
Epifani, E.,Lapucci, A.,Macchia, B.,Macchia, F.,Tognetti, P.,et al.
, p. 254 - 259 (2007/10/02)
In order to obtain a better understanding of the effects that structural parameters have on the changes of adrenergic activity when 1-aryl-2-aminoethanol derivatives are converted into their corresponding 2-arylmorpholine cyclic analogues, we synthesized 1-(2,5-dimethoxyphenyl)-2-aminoethanol derivatives 5-7 and their morpholine analogues 8-10.The preferred conformations of amino alcohols and their cyclic analogues have been determined through an 1H NMR and IR study.Compounds 5 and 6 showed both α-stimulating and α-blocking activity on rat vas deferens, the effect depending on the concentration employed; on the same isolated tissue, N-isopropyl derivative 7 and the morpholine analogues 8-10 exhibited only α-blocking activity.As for the β-adrenergic activity, only the open-chain compound 7 possessed a moderate blocking effect on isolated guinea pig atria.The results of this work seem to indicate that the changes of pharmacological activity involved in the transformation of the adrenergic drugs into their morpholine analogues are influenced more by characteristic features of the aromatic moiety than by the ethanolamine or propanolamine structure of the drug.
