6180-80-9

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
(4-aminophenyl)(4-methylphenyl)methanone is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals due to its unique molecular structure that can be further modified to create a range of different compounds.
Used in Dyes and Pigments Production:
(4-aminophenyl)(4-methylphenyl)methanone is also utilized in the production of dyes and pigments, where its chemical properties allow for the creation of a variety of colors and shades.
Used in Research and Development:
(4-aminophenyl)(4-methylphenyl)methanone has potential applications in research and development, particularly in the field of organic chemistry, where it can be used to study and develop new chemical reactions and processes.

Upstream product

• 5350-47-0 (4-methylphenyl)(4-nitrophenyl)methanone 
• 150-13-0 4-amino-benzoic acid 
• 108-88-3 toluene 
• 6833-18-7 4-methyl-N-phenylbenzamide 
• 636-98-6 p-nitrobenzene iodide 
• 5720-05-8 4-methylphenylboronic acid 
• 13939-06-5 molybdenum hexacarbonyl 
• 540-37-4 p-aminoiodobenzene 
• 589-18-4 4-Methylbenzyl alcohol 
• 62-53-3 aniline 
• 108-90-7 chlorobenzene 
• 99-94-5 p-Toluic acid 
• 122-04-3 4-nitro-benzoyl chloride 
• 5395-79-9 4'-methyl-4-chlorobenzophenone 

Downstream Products

• 71968-59-7 C₂₇H₂₃ClN₄ 
• 71968-61-1 C₂₈H₂₆N₄O 
• 71968-63-3 C₂₇H₂₃BrN₄ 
• 71968-64-4 C₂₉H₂₈N₄ 
• 71968-81-5 C₂₉H₂₈N₄ 
• 71968-73-5 C₂₈H₂₅ClN₄ 
• 71968-80-4 4-[{[1-(4-Amino-phenyl)-1-p-tolyl-meth-(Z)-ylidene]-hydrazono}-(4-methoxy-phenyl)-methyl]-2-methyl-phenylamine 
• 71961-32-5 C₂₈H₂₆N₄ 
• 71968-60-0 C₂₇H₂₄N₄ 
• 122001-56-3 4-Methyl-4'-(1H-pyrrol-1-yl)benzophenone 
• 122001-59-6 p-Methyl-α-<4-(1H-pyrrol-1-yl)phenyl>benzyl alcohol 
• 122001-60-9 1-[4-(Bromo-p-tolyl-methyl)-phenyl]-1H-pyrrole 

Relevant academic research and scientific papers

Ligand-free Palladium-Catalyzed Carbonylative Suzuki Coupling of Aryl Iodides in Aqueous CH3CN with Sub-stoichiometric Amount of Mo(CO)6 as CO Source

A new method for the synthesis of diaryl and heterodiaryl ketones has been established based on the palladium-catalyzed carbonylative Suzuki coupling approach with sub-stoichiometric Mo(CO)6 as CO source. Using 0.5 mol% of Pd(TFA)2 as catalyst, 0.5 equivalent of Mo(CO)6 as solid carbonyl reagent and 3 equivalent of K3PO4 as base, a wide range of functionalized (hetero)aryl iodides and (hetero)aryl boronic acids could smoothly proceed the carbonylative cross-coupling reaction in aqueous CH3CN at 50 °C, affording the corresponding ketones in good to excellent yields. The newly developed method was easy to operate under mild conditions with high efficiency. (Figure presented.).

Coumarin-surfactant modified polyoxometalate catalyzed cross dehydrogenative coupling of benzyl alcohol with the: Para -C-H of unprotected aniline

This paper presents a novel method for synthesizing para-aminobenzophenone and its derivatives (p-ABPs) using a coumarin-surfactant modified polyoxometalate as the catalyst. Preliminary mechanistic studies indicate that the reaction has undergone an oxidative cross dehydrogenative coupling process. This method has the advantages of an easy process, a convenient raw material source, safe and green oxidants, and tolerances of several functional groups.

Studies on the Insecticidal Activities of Some New N-Benzoyl-N'-Arylureas

This paper reports the synthesis and the insecticidal activities of some N-benzoyl-N'-arylureas 4-arylsubstituted with alkylated or halogenated aroyl moieties. The compounds, tested against some representative insect species, displayed very high activity against Aedes aegypti, especially the halosubstituted derivatives. None of the newly synthesized compounds showed genotoxic activity in the Bacillus subtilis rec-assay and in the Salmonella-microsome test.

STUDIES IN TRIFLUOROMETHANESULPHONIC ACID-IV KINETICS AND MECHANISM OF ACYLATION OF AROMATIC COMPOUNDS

A detailed kinetic study has been made of acylation reactions in solvent trifluoromethane sulphonic acid (CF3SO3H) using carboxylic acids as the electrophilic species involved.These species were shown to be probably the protonated form of the mixed anhydride.The reactions show high substrate selectivity characterised by high negative values of p+.Substituents in the carboxylic acids have a relatively small influence on the reactions rates due to a cancellation of substituents effects on the protonation of the mixed anhydride with those operating on the subsequent slow reaction of these species with the aromatic substrate.Anomalous effects were found for certain ortho substituents.The overall mechanism is discussed in terms of polar and steric effects in conjunction with the competing protonation of the aromatic bases, together with evidence from isotope effects.