61831-29-6

Upstream product

• 1780-17-2 quinolin-2-ylmethanol 
• 100-44-7 benzyl chloride 
• 98-88-4 benzoyl chloride 
• 532-32-1 sodium benzoate 
• 5632-15-5 quinolin-2-ylmethylbromide 
• 1076-28-4 2-methylquinoline N-oxide 
• 67-66-3 chloroform 
• 612-62-4 2-Chloroquinoline 
• 14135-39-8 [(benzoyloxy)methyl]zinc iodide 
• 91-63-4 2-methylquinoline 
• 100-52-7 benzaldehyde 
• 100-51-6 benzyl alcohol 

Downstream Products

• 91-63-4 2-methylquinoline 
• 1780-17-2 quinolin-2-ylmethanol 

Relevant academic research and scientific papers

Synthesis of benzyl esters from the commercially available alcohols catalyzed by TBAI via C(sp3)-H bond functionalization

A direct esterification of alcohols catalyzed by TBAI via C(sp3)-H bond functionalization was achieved under mild and clean conditions. A series of benzyl esters were obtained in good to excellent yields via the C(sp3)-H bond functionalization of alkyl-substituted azaarenes.

Synthesis of 2-Pyridinemethyl Ester Derivatives from Aldehydes and 2-Alkylheterocycle N-Oxides via Copper-Catalyzed Tandem Oxidative Coupling-Rearrangement

Successful benzylic C(sp3)-H acyloxylation of 2-alkylpyridine, 2-alkylpyrazine, and 2-alkylthiazole compounds was achieved using simple aldehydes. This was carried out via a copper-catalyzed tandem reaction, involving oxidative esterification followed by O-atom transfer of the resultant high yield formed Boekelheide intermediate. The method enables the preparation of functional heterocycles and the desymmetrization of 2,6-dialkylpyridines for efficient synthesis of dissymmetric pincer ligands, thus offering a new life for more practical Boekelheide rearrangement.

Bu4NI-catalyzed benzylic acyloxylation of alkylarenes with aromatic aldehydes

An nBu4NI-catalyzed benzylic C-H acyloxylation of alkylarenes with readily available aromatic aldehydes has been developed. These reactions occur under mild and clean reaction conditions using tert-butyl hydroperoxide as the green terminal oxid

Hydroxymethylations of aryl halides by Pd-catalyzed cross-couplings with (benzoyloxy)methylzinc iodide - Scope and limitations of the reaction

Palladium-catalyzed cross-coupling reactions of (benzoyloxymethyl)zinc iodide with diverse (het)aryl halides leading to (benzoyloxymethyl)(het)arenes were studied to define the scope of this reaction. It has been found that this reaction is only applicable for electron-deficient aryl halides and the most efficient it is for 2-halopyridines and 4-halopyrimidines. Deprotection of the intermediates gives (hydroxymethyl)pyridines and -pyrimidines in high yields. Georg Thieme Verlag Stuttgart.