62137-63-7Relevant academic research and scientific papers
Bifunctional catalysts stabilized on nanocrystalline magnesium oxide for one-pot synthesis of chiral diols
Choudary, Boyapati M.,Jyothi, Karangula,Roy, Moumita,Kantam, Mannepalli L.,Sreedhar, Bojja
, p. 1471 - 1480 (2004)
New bifunctional catalysts composed of PdCl42-, OsO42- and OsO42-, WO 42- designed and prepared by a counterionic stabilization technique involving the reactions of Na2PdCl4-K 2OsO4 and K2OsO4-Na 2WO4 with nanocrystalline MgO are well characterized. These bifunctional catalysts, NAP-Mg-PdOs and NAP-Mg-OsW perform tandem Heck asymmetric dihydroxylation and asymmetric dihydroxylation-N-oxidation reactions, respectively, in the presence of the chiral ligand 1,4-bis(9-o- dihydroquinidinyl)phthalazine [(DHQD)2PHAL] in a single pot. It is quite impressive to note that H2O2 is used as a terminal oxidant to provide N-methylmorpholine N-oxide (NMO) in situ by the oxidation of N-methylmorpholine (NMM) in the asymmetric dihydroxylation-N-oxidation catalyzed by NAP-Mg-OsW.
The enhanced asymmetric hydrogenation of unsymmetrical benzils to hydrobenzoin catalyzed by organosoluble zirconium phosphonate-immobilized ruthenium catalyst
Du, Yu,Feng, Dandan,Wan, Jingwei,Ma, Xuebing
, p. 49 - 58 (2014/06/09)
In this article, a successful design on translating a heterogeneous catalysis of chiral zirconium phosphonate-supported ruthenium catalyst into a homogeneous system was developed by the covalent attachment of chiral (R,R)-1,2-diphenyl-ethylenediamine [(R,R)-DPEN] into the backbone of zirconium phosphonate with the different arm lengths (n = 2, 4, 6) and immobilization of [RuCl2(p-cymene)]2. Their catalytic performances in the homogeneous asymmetric transfer hydrogenation of unsymmetrical benzils with m- and p-substituents were enhanced, and the excellent activities (>97.1% conv.), diastereomeric and enantiomeric purities (syn/anti = 11.0-29.4, 91.8-99.2%ee syn) were achieved. These homogeneous supported Ru catalysts could be quantitatively and readily recovered by addition of ethyl acetate and centrifugation by solid/liquid separation, and be reused for five times without significant loss of their catalytic performances with 97.0% conv.; 95.6% syn and syn/anti = 20.7.
Anionic Zirconaoxiranes as Nucleophilic Aldehyde Equivalents. Application to Intermolecular Pinacol Cross Coupling
Askham, Fredric R.,Carroll, Kevin M.
, p. 7328 - 7329 (2007/10/02)
Selective intermolecular pinacol cross coupling is achieved by reaction of anionic zirconaoxiranes with aromatic aldehydes and ketones, thereby providing an efficient route to unsymmetrical vicinal diols.
