62172-89-8

Basic information

• Product Name: 4-(Methoxymethyl)-benzenemethanol
• Synonyms: (4-Methoxymethyl-phenyl)-methanol
• CAS NO: 62172-89-8
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.19038
• Mol File: 62172-89-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 152 °C(Press: 16 Torr)
• Appearance: /
• Density: 1.076 g/cm3(Temp: 17 °C)
• PKA: 14.34±0.10(Predicted)
• CAS DataBase Reference: 4-(Methoxymethyl)-benzenemethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Methoxymethyl)-benzenemethanol(62172-89-8)
• EPA Substance Registry System: 4-(Methoxymethyl)-benzenemethanol(62172-89-8)

Safety Data

• Hazardous Substances Data: 62172-89-8(Hazardous Substances Data)

Usage

General Description

4-(Methoxymethyl)-benzenemethanol, also known as p-methoxymethylphenylmethanol, is an organic compound with the molecular formula C9H12O2. It is a white solid with a sweet, floral odor and is used as a fragrance ingredient in perfumes and personal care products. 4-(Methoxymethyl)-benzenemethanol is also used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is primarily derived from the organic compound benzene and is commonly produced using chemical synthesis methods. 4-(Methoxymethyl)-benzenemethanol is considered to be relatively safe for use in consumer products, but should be handled with caution and in accordance with safety protocols.

Upstream product

• 67-56-1 methanol 
• 71831-21-5 4-(bromomethyl)benzyl alcohol 
• 67003-50-3 4-(Methoxymethyl)benzoic acid 
• 589-29-7 p-xylylene glycol 
• 74-88-4 methyl iodide 
• 1719-82-0 p-methoxymethylbenzoic acid methyl ester 
• 120-61-6 1,4-benzenedicarboxylic acid dimethyl ester 
• 77-78-1 dimethyl sulfate 
• 52889-83-5 1-(chloromethyl)-4-(methoxymethyl)benzene 
• 538316-01-7 1,1-dimethylethyl 4-(methoxymethyl)benzoate 
• 93943-06-7 4-(methoxymethyl)benzaldehyde 

Downstream Products

• 52889-83-5 1-(chloromethyl)-4-(methoxymethyl)benzene 
• 934667-43-3 1-(4-(triisopropylsilanyloxymethyl)phenyl)-3-(4-methoxymethylphenyl)-propan-2-one 
• 934667-49-9 2-(4-(triisopropylsiloxymethyl)phenyl)-5-(4-(methoxymethyl)phenyl)-3,4-diphenylcyclopenta-2,4-dienone 
• 934667-50-2 2-(4-(triisopropylsiloxymethyl)phenyl)-5-(4-(methoxymethyl)phenyl)-3,4-bis-(4-bromophenyl)cyclopenta-2,4-dienone 
• 67003-50-3 4-(Methoxymethyl)benzoic acid 
• 93943-06-7 4-(methoxymethyl)benzaldehyde 
• 119991-79-6 4-(methoxymethyl)benzyl acetate 
• 54549-74-5 4-(acetoxymethyl)benzaldehyde 
• 73291-09-5 4-chloromethylbenzaldehyde 
• 95349-71-6 1-(bromomethyl)-4-(methoxymethyl)benzene 
• 623-27-8 terephthalaldehyde, 

Relevant articles and documents

ANTIBIOTIC RESISTANCE BREAKERS

The invention relates to antibiotic compounds of formula (A1) and pharmaceutically acceptable salts, solvates, tautomers and combinations thereof, wherein X and L are optional linkers and one of RA or R1 comprises Ar1, wherein Ar1 is an antibiotic resistance breaker moiety which comprises an optionally substituted C6-10 aryl, C7-13 aralkyl, C5-10 heteroaryl, C6-13 heteroaralkyl, C5-10 heterocyclyl, C6-13 heterocyclalkyl, C3-10 carbocyclyl, C4-13 carbocyclalkyl, -C(=NR')-NR'R'' or –CH2- CH=CH2 group; wherein after administration of the compound to a bacterial infection this moiety reduces or prevents efflux. The invention also discloses pharmaceutical compositions comprising compounds of formula (A1) and the use of such compounds as medicaments, in particular, to treat bacterial infections, such as drug-resistant bacterial infections.

Synthesis of heterosubstituted hexaarylbenzenes via asymmetric carbonylative couplings of benzyl halides

Asymmetric carbonylative couplings of benzyl halldes have been shown to give heterosubstituted 1,3-diarylacetones In moderate to high yields. These asymmetric ketones were converted via Knoevenagel condensations to tetraarylcyclopentadienones, and further

Synthesis and Preliminary Biological Evaluation of 6-O-[11C]-[(methoxymethyl)benzyl]guanines, New Potential PET Breast Cancer Imaging Agents for the DNA Pepair Protein AGT

Novel radiolabeled O6-benzylguanine derivatives, 6-O-[11C]-[(methoxymethyl)benzyl]guanines ([11C]p-O6-MMBG, 1a; [11C]m-O6-MMBG, 1b; ([11C]o-O6-MMBG, 1c), have been synthesized for evaluation as new potential positron emission tomography (PET) breast cancer imaging agents for DNA repair protein, O6-alkylguanine-DNA alkyltransferase (AGT).