93943-06-7

Basic information

• Product Name: 4-(Methoxymethyl)-benzaldehyde
• Synonyms: 4-(Methoxymethyl)-benzaldehyde
• CAS NO: 93943-06-7
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.17
• Mol File: 93943-06-7.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(Methoxymethyl)-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Methoxymethyl)-benzaldehyde(93943-06-7)
• EPA Substance Registry System: 4-(Methoxymethyl)-benzaldehyde(93943-06-7)

Safety Data

• Hazardous Substances Data: 93943-06-7(Hazardous Substances Data)

Upstream product

• 100-97-0 hexamethylenetetramine 
• 52889-83-5 1-(chloromethyl)-4-(methoxymethyl)benzene 
• 46316-11-4 α,α,α'-trimethoxy-p-xylene 
• 106-42-3 para-xylene 
• 73291-09-5 4-chloromethylbenzaldehyde 
• 124-41-4 sodium methylate 
• 62172-89-8 4-methyloxymethylhydroxymethylhydroxymethylcyclohexane 
• 52010-97-6 4-(hydroxylmethyl)benzaldehyde 
• 74-88-4 methyl iodide 
• 7398-44-9 1-chloromethyl-4-dichloromethyl-benzene 
• 874-86-2 4-cyanobenzyl chloride 
• 80413-59-8 p-bromomethylbenzal bromide 
• 1571-08-0 methyl 4-formylbenzoate 
• 174316-23-5 4-(1,3-dioxolan-2-yl)benzyl tosylate 

Downstream Products

• 855383-33-4 (+/-)-α-hydroxy-4-methoxymethyl-bibenzyl 
• 141200-10-4 5-{4-[(E)-3-(4-Methoxymethyl-phenyl)-acryloyl]-benzyl}-thiazolidine-2,4-dione 
• 851393-55-0 2-(4-methoxymethylphenyl)-1,3-dimethylimidazolidine 
• 874486-67-6 (E,E)-1,4-bis[4-(methoxymethyl)styryl]benzene 
• 1426998-74-4 C₂₅H₂₄N₂O₄ 
• 1246935-92-1 6-(4-methoxymethyl-phenyl)-fulvene 
• 851393-67-4 4-[5-(4-formylphenyl)pentyl]benzaldehyde 
• 23229-38-1 1,3-dimethyl-2-p-tolyl-imidazolidine 
• 6853-57-2 4-pentylbenzaldehyde 

Relevant articles and documents

COMPOUNDS FOR THE REDUCTION OF THE DELETERIOUS ACTIVITY OF EXTENDED NUCLEOTIDE REPEAT CONTAINING GENES

Aspects of the present disclosure include methods of reducing the deleterious impact of a target gene in a cell, such as the deleterious activity of a mutant extended nucleotide repeat (NR) containing target gene in a cell by contacting the cell with an effective amount of a tetrahydrocarbazole compound. The deleterious activity (e.g., toxicity and/or dis-functionality of products encoded thereby) of a mutant extended NR containing target gene may be reduced, e.g., by reducing (and in some instances differentially, including selectively, reducing) the production or activity of toxic expression products (e.g., RNA or protein) encoded by the target gene. Kits and compositions for practicing the subject methods are also provided.

Efficient synthesis of cryptophycin-52 and novel para- Alkoxymethyl unit A analogues

Cryptophycins are a family of highly cytotoxic, cyclic depsipeptides. They display antitumour activity that is largely maintained for multidrug-resistant tumour cells. Cryptophycins are composed of four building blocks (units A-D) that correspond to the respective amino and hydroxy acids. A new synthetic route to unit A allows the selective generation of all four stereogenic centres in a short, efficient and reliable synthesis and con-tributes to an easier and faster synthesis of cryptophycins. The first two stereogenic centres are introduced by a catalytic asymmetric dihydroxylation, whereas the remaining two stereogenic centres are introduced with substrate control of diastereoselectivity. The stereogenic diol function also serves as the epoxide precursor. The approach was used to synthesise the native unit A building block as well as three paraalkoxymethyl analogues from which cryptophycin-52 and three analogous cryptophycins were prepared. Macrocyclisation of the seco-depsipeptides was based on ring-closing metathesis.

Synthetic protocols and building blocks for molecular electronics

Simple and readily accessible aryl bromides are useful building blocks for thiol end-capped molecular wires. Thus, 4-bromophenyl tert-butyl sulfide and 1-bromo-4-(methoxymethyl)benzene serve as precursors for a variety of oligo(phenylenevinylene) and olig