67003-50-3

Basic information

• Product Name: 4-(METHOXYMETHYL)BENZOIC ACID
• Synonyms: 4-(methoxymethyl)benzoic acid(SALTDATA: FREE)
• CAS NO: 67003-50-3
• Molecular Formula: C₉H₁₀O₃
• Molecular Weight: 166.18
• Mol File: 67003-50-3.mol
• Article Data: 8

Chemical Properties

• Melting Point: 123 °C
• Boiling Point: 281.8°Cat760mmHg
• Flash Point: 112.5°C
• Appearance: /
• Density: 1.177g/cm³
• Vapor Pressure: 0.00166mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.19±0.10(Predicted)
• CAS DataBase Reference: 4-(METHOXYMETHYL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(METHOXYMETHYL)BENZOIC ACID(67003-50-3)
• EPA Substance Registry System: 4-(METHOXYMETHYL)BENZOIC ACID(67003-50-3)

Safety Data

• Hazardous Substances Data: 67003-50-3(Hazardous Substances Data)

Usage

General Description

4-(Methoxymethyl)benzoic acid is a chemical compound that contains a benzene ring with a carboxylic acid group and a methoxymethyl group attached to it. It is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. 4-(METHOXYMETHYL)BENZOIC ACID has the potential to be utilized as a building block in the development of new drugs and other biologically active molecules due to its structural properties and reactivity. Additionally, it is also used in the production of materials such as adhesives and coatings, making it a versatile chemical with multiple industrial applications.

InChI:InChI=1/C9H10O3/c1-12-6-7-2-4-8(5-3-7)9(10)11/h2-5H,6H2,1H3,(H,10,11)

Upstream product

• 1917-60-8 5-methoxymethyl-2-furancarboxylic acid 
• 74-85-1 ethene 
• 93943-06-7 4-(methoxymethyl)benzaldehyde 
• 62172-89-8 4-methyloxymethylhydroxymethylhydroxymethylcyclohexane 
• 6232-88-8 4-bromomethylbenzoic Acid 
• 538316-01-7 1,1-dimethylethyl 4-(methoxymethyl)benzoate 
• 67-56-1 methanol 
• 52889-83-5 1-(chloromethyl)-4-(methoxymethyl)benzene 

Downstream Products

• 538316-01-7 1,1-dimethylethyl 4-(methoxymethyl)benzoate 
• 1571-08-0 methyl 4-formylbenzoate 
• 623-27-8 terephthalaldehyde, 
• 119991-79-6 4-(methoxymethyl)benzyl acetate 
• 52889-83-5 1-(chloromethyl)-4-(methoxymethyl)benzene 
• 54549-74-5 4-(acetoxymethyl)benzaldehyde 
• 73291-09-5 4-chloromethylbenzaldehyde 
• 93943-06-7 4-(methoxymethyl)benzaldehyde 
• 62172-89-8 4-methyloxymethylhydroxymethylhydroxymethylcyclohexane 
• 619-66-9 4-Carboxybenzaldehyde 
• 1719-82-0 p-methoxymethylbenzoic acid methyl ester 

Relevant articles and documents

DIELS-ALDER REACTIONS CATALYZED BY LEWIS ACID CONTAINING SOLIDS: RENEWABLE PRODUCTION OF BIO-PLASTICS

The present disclosure is related to silica-based Lewis acid catalysts, being essentially devoid of strong Br?nsted acid character, and their ability to effect the [4+2] cycloaddition and dehydrative aromatization of dienes and dienophiles containing oxygenated substituents to form substituted benzene products. In some embodiments, the processes comprise contacting biomass-derived substrates with ethylene to form terephthalic acid and its derivatives.

Preparation and reactivity of polystyrene-supported iodosylbenzene: Convenient recyclable oxidizing reagent and catalyst

A facile preparation of novel polystyrene-supported iodosylbenzene (PS-ISB, loading of IO up to 1.50 mmol/g) from iodopolystyrene is described. This resin has been successfully used for efficient oxidation of a diverse collection of alcohols to aldehydes and ketones in the presence of BF3OEt 2. PS-ISB can also be employed as efficient co-catalyst in combination with RuCl3 in the catalytic oxidation of alcohols and aromatic hydrocarbons, respectively, to corresponding carboxylic acids and ketones using Oxone as the stoichiometric oxidant. Georg Thieme Verlag Stuttgart ? New York.

Oxidation of benzylic alcohols and ethers to carbonyl derivatives by nitric acid in dichloromethane

Nitric acid in dichloromethane may be successfully employed for the oxidation of benzylic alcohols and ethers to the corresponding carbonyl compounds. The proposed method proved to be of general applicability, affording very good yields of aldehydes and ketones and showing interesting chemoselectivity in many instances, allowing competitive aromatic nitration to be avoided, as well as - in the case of aldehydes - any further oxidation to carboxylic acids. The reaction probably proceeds by a radical mechanism, the active species in the oxidation process being NO2. Competitive formation of nitro esters was observed in some cases, whereas poor results were obtained with allylic and non-benzylic substrates. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.