622-84-4

Basic information

• Product Name: 1-FORMYL-2-PHENYLHYDRAZINE
• Synonyms: 1-FORMYL-2-PHENYLHYDRAZINE;2-PHENYLHYDRAZINE-1-CARBOXALDEHYDE;AURORA KA-348;TIMTEC-BB SBB008261;1-formyl-2-phenyl-hydrazin;2-Formyl-1-phenylhydrazine;Fenylhydrazid kyseliny mravenci;fenylhydrazidkyselinymravenci
• CAS NO: 622-84-4
• Molecular Formula: C₇H₈N₂O
• Molecular Weight: 136.15
• Mol File: 622-84-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 142-143℃
• Boiling Point: 226.6℃
• Flash Point: 103.1℃
• Appearance: /
• Density: 1.183
• Vapor Pressure: 0.0811mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: 2-8°C
• PKA: 12.94±0.23(Predicted)
• CAS DataBase Reference: 1-FORMYL-2-PHENYLHYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-FORMYL-2-PHENYLHYDRAZINE(622-84-4)
• EPA Substance Registry System: 1-FORMYL-2-PHENYLHYDRAZINE(622-84-4)

Safety Data

• Hazardous Substances Data: 622-84-4(Hazardous Substances Data)

Usage

General Description

1-Formyl-2-phenylhydrazine is a chemical compound with the molecular formula C8H9N3O. It is a hydrazine derivative with a formyl group and a phenyl group attached to the hydrazine nitrogen atoms. 1-FORMYL-2-PHENYLHYDRAZINE is used in organic synthesis and as a reagent in various chemical reactions. It has also been investigated for its potential applications in medicinal chemistry, particularly in the development of new pharmaceuticals. 1-Formyl-2-phenylhydrazine is known to be toxic and should be handled with care in a laboratory setting.

InChI:InChI=1/C7H8N2O/c10-6-8-9-7-4-2-1-3-5-7/h1-6,9H,(H,8,10)

Upstream product

• 17308-74-6 N-nitroso formanilide 
• 100-63-0 phenylhydrazine 
• 22071-69-8 formic acid-(N-nitroso-p-toluidide) 
• 64-17-5 ethanol 
• 109-94-4 formic acid ethyl ester 
• 141-52-6 sodium ethanolate 
• 103-70-8 Formanilid 
• 64-18-6 formic acid 
• 6228-39-3 1-(4-methylpentan-2-ylidene)-2-phenylhydrazine 
• 99466-36-1 3,4-dihydro-2H-naphthalen-1-one-phenylhydrazone 
• 26660-87-7 5-Acetyl-1,5-diphenyl-formazan 
• 104743-78-4 2-methyl-pent-2-enal-phenylhydrazone 
• 124-38-9 carbon dioxide 
• 107-31-3 Methyl formate 

Downstream Products

• 13423-60-4 1-phenyl-1H-1,2,4-triazole 
• 120318-33-4 1,4-diphenyl-1,2,4-triazoline-5-thione 
• 2879-44-9 Formic acid N'-(4-tricyanovinyl-phenyl)-hydrazide 
• 226724-38-5 C₁₄H₂₁N₃O₂ 
• 226724-39-6 C₁₆H₂₅N₃O₂ 
• 857796-64-6 formic acid-(N'-nitroso-N'-phenyl-hydrazide) 
• 79984-61-5 formic acid-[N'-(4-thiocyanato-phenyl)-hydrazide] 
• 38604-71-6 formic acid-(N',N'-diphenyl-hydrazide) 
• 14575-62-3 5-methyl-1-phenyl-1,2-dihydro-pyrazol-3-one 
• 89-25-8 edaravone 
• 69933-27-3 4-hexyl-2-phenyl-2,4-dihydro-[1,2,4]triazol-3-one 
• 226724-43-2 4-(4-hexyl-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl)-benzenesulfonyl chloride 
• 226724-44-3 4-(4-octyl-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl)-benzenesulfonyl chloride 
• 21434-16-2 1-phenyl-1H-1,2,4-triazol-5-one 

Relevant articles and documents

The Base-Promoted Annulation of 2-Hydrazinyl Pyridine and CO2 toward Triazolones

A base-promoted annulation of 2-hydrazinyl pyridine and atmospheric pressure of CO2 has been developed in the presence of silane as reducing reagent, affording a series of triazolones in moderate to excellent yields. CO2 served as a carbonyl source in this transfomation. Moreover, benzamidrazones also worked well under this procedure. Thus, it represents a green, sustainable and straightforward pathway to access triazolone frameworks. (Figure presented.).

An eco-benign and highly efficient procedure for N-acylation catalyzed by heteropolyanion-based ionic liquids using carboxylic acid under solvent-free conditions

An eco-benign and highly efficient route for N-acylation of amines has been developed by treating amines with corresponding carboxylic acids in the presence of 2 mol % of heteropolyanion-based ionic liquids as catalysts under solvent-free conditions. This practical reaction could tolerate a wide range of substrates. Thus, various N-acylation products including N-acyl α-amino acid derivatives were obtained in moderate to excellent yields at 70 C to 120 C. Moreover, recycling studies revealed that heteropolyanion-based ionic liquids were easily reusable for this N-acylation. This method provides a green and much improved protocol over the existing methods.

N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES

Novel N-phenyl-1,1,1-trifluoromethanesulfonamide compounds useful for controlling endo and/or ectoparasites in the environment are provided, together with methods of making the same, and methods of using the inventive compounds to treat parasite infestations in vivo and ex vivo.