62456-45-5Relevant articles and documents
Synthesis and reactivity of substituted alkoxymethylphosphonites and their derivatives
Prishchenko, Andrey A.,Livantsov, Mikhail V.,Novikova, Olga P.,Livantsova, Ludmila I.,Petrosyan, Valery S.
experimental part, p. 281 - 289 (2012/07/28)
Alkoxy-substituted methylphosphonites and their derivatives are prepared using an organomagnesium method of synthesizing the organophosphorus compounds and alkoxymethylation of various PH acids and their derivatives. Also, certain properties of these promising compounds as important precursors of new functionalized organophosphorue compounds with alkoxymethyl fragments are presented.
Enantioselective copper-catalyzed O-H insertion of α-diazo phosphonates
Zhu, Shou-Fei,Chen, Wang-Qiao,Zhang, Qian-Qian,Mao, Hong-Xiang,Zhou, Qi-Lin
scheme or table, p. 919 - 922 (2011/06/17)
A copper-catalyzed asymmetric O-H insertion of -di-azo phosphonates with alcohols by using chiral spiro bisoxazoline ligands was developed. The insertion reaction exhibited good yields (up to 89%) with high enantioselectivities (up to 98% ee) and provided
CHEMICAL SHIFT NON-EQUIVALENCE IN THE NMR SPECTROSCOPY OF DIALKYL α-HYDROXYBENZYL- AND DIALKYL α-METHOXYBENZYLPHOSPHONATES AND THE CRYSTAL STRUCTURE OF DIMETHYL α-CHLOROMETHYL-α-HYDROXYBENZYLPHOSPHONATE
Hudson, Harry R.,McPartlin, Mary,Matthews, Ray W.,Powell, Harold R.,Yusuf, Ramon O.,et al.
, p. 239 - 244 (2007/10/02)
Single crystal X-ray diffraction of dimethyl α-chloromethyl-α-hydroxybenzylphosphonate shows the compound to exist as hydrogen-bonded dimers in the solid state.In solution, 1H and 13C nmr spectroscopy reveal chemical shift non-equivalence of the corresponding nuclei in the two alkoxy groups of dialkyl α-hydroxybenzyl- and dialkyl α-methoxybenzylphosphonates, an effect that is attributed primarily to the presence of the chiral α-carbon atom, although restriction of rotation about the P-Cα bond by intermolecular hydrogen-bonding may also be a factor in the α-hydroxy compounds.Chemical shift non-equivalence of the α-halogenomethyl protons in dimethyl α-halogenomethyl-α-hydroxybenzylphosphonates is significantly greater for the chloro- than for the bromo-compound.Keywords: X-ray crystal structure; nmr spectroscopy; chemical shift non-equivalence; α-hydroxyphosphonates; α-methoxyphosphonates.