63012-04-4

Basic information

• Product Name: (3-bromophenyl)(phenyl)methanol
• Synonyms: (3-Bromophenyl)phenylmethanol
• CAS NO: 63012-04-4
• Molecular Formula: C₁₃H₁₁BrO
• Molecular Weight: 263.1298
• Mol File: 63012-04-4.mol
• Article Data: 35

Chemical Properties

• Boiling Point: 372.2°C at 760 mmHg
• Flash Point: 178.9°C
• Density: 1.435g/cm³
• Vapor Pressure: 3.38E-06mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: (3-bromophenyl)(phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3-bromophenyl)(phenyl)methanol(63012-04-4)
• EPA Substance Registry System: (3-bromophenyl)(phenyl)methanol(63012-04-4)

Safety Data

• Hazardous Substances Data: 63012-04-4(Hazardous Substances Data)

Usage

General Description

The chemical compound (3-bromophenyl)(phenyl)methanol, also known as 3-bromo-α-tolylbenzyl alcohol, is a benzyl alcohol derivative with the molecular formula C13H11BrO. It is a white to off-white crystalline powder with a molecular weight of 257.13 g/mol. (3-bromophenyl)(phenyl)methanol is primarily used in the pharmaceutical and organic synthesis industries as a building block and intermediate for the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a reagent in chemical reactions and as a starting material for the preparation of other functionalized benzyl alcohol derivatives. Additionally, (3-bromophenyl)(phenyl)methanol has potential applications in the field of materials science and polymers due to its structural versatility and reactivity. Overall, this compound plays an important role in the synthesis of diverse organic compounds and has various potential industrial applications.

Upstream product

• 1016-77-9 3-bromobenzophenone 
• 3132-99-8 m-bromobenzoic aldehyde 
• 108-36-1 1,3-dibromobenzene 
• 100-52-7 benzaldehyde 
• 17878-47-6 (3-bromophenyl)trimethylsilane 
• 934-56-5 trimethyl(phenyl)stannane 
• 16002-63-4 phenylmagnesium iodide 
• 100-59-4 phenylmagnesium chloride 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 3262-89-3 triphenylboroxine 
• 71-43-2 benzene 
• 1711-09-7 3-bromobenzoyl chloride 
• 108-86-1 bromobenzene 
• 98-80-6 phenylboronic acid 

Downstream Products

• 111531-41-0 (+/-)-phthalic acid mono-(3-bromo-benzhydryl ester) 
• 1016-77-9 3-bromobenzophenone 
• 63012-04-4 (-)-(3-bromophenyl)phenylmethanol 
• 86997-98-0 (3-(methylamino)phenyl)(phenyl)methanol 
• 1555554-69-2 2-(((3-bromophenyl)(phenyl)methyl)thio)acetamide 
• 1555555-14-0 2-(((3-bromophenyl)(phenyl)methyl)sulfinyl)acetamide 
• 1426943-25-0 3''-benzyl-2'-isobutyl-3-isopropyl[1,1':4',1'']terphenyl 
• 173394-24-6 (3-benzylphenyl)boronic acid 
• 324008-21-1 2-(3-bromophenyl)-2-phenylacetonitrile 
• 1280733-16-5 (3-benzyl-phenyl)-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-methanol 

Relevant articles and documents

Tunable System for Electrochemical Reduction of Ketones and Phthalimides

Herein, we report an efficient, tunable system for electrochemical reduction of ketones and phthalimides at room temperature without the need for stoichiometric external reductants. By utilizing NaN3 as the electrolyte and graphite felt as both the cathode and the anode, we were able to selectively reduce the carbonyl groups of the substrates to alcohols, pinacols, or methylene groups by judiciously choosing the solvent and an acidic additive. The reaction conditions were compatible with a diverse array of functional groups, and phthalimides could undergo one-pot reductive cyclization to afford products with indolizidine scaffolds. Mechanistic studies showed that the reactions involved electron, proton, and hydrogen atom transfers. Importantly, an N3/HN3 cycle operated as a hydrogen atom shuttle, which was critical for reduction of the carbonyl groups to methylene groups.

SMALL MOLECULE MODULATORS OF IL-17

The present invention relates to a compound according to formula I and pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention further relates to, to said compounds for use in therapy, to pharmaceutical compositions comprising said

[Ir(COD)Cl]2/tris(2,4-di-t-butylphenyl)phosphite-catalyzed addition reactions of arylboronic acids with aldehydes

[Ir(COD)Cl]2/tris(2,4-di-t-butylphenyl)phosphite-catalyzed addition reactions of arylboronic acids with aldehydes were described. The Ir(I) catalyst, generated from [Ir(COD)Cl]2 and tris(2,4-di-t-butylphenyl)phosphite, was an efficient catalyst system for the addition reactions of a variety of arylboronic acids with aromatic and aliphatic aldehydes. The easy availability of the catalyst and good yields make these reactions potentially useful in organic synthesis.