6303-18-0 Usage
General Description
Pentane-1-sulfonyl chloride, also known as n-pentane-1-sulfonyl chloride, is a chemical compound with the molecular formula C5H11ClO2S. It is a colorless to pale yellow liquid that is primarily used as a reagent in organic synthesis. Pentane-1-sulfonyl chloride is a versatile compound, often employed in the production of pharmaceuticals and agrochemicals as well as in the preparation of sulfonamide antibiotics and other organic compounds. It is a highly reactive compound, capable of reacting with a wide range of functional groups, and is commonly used as a chlorinating agent in laboratory and industrial settings. Additionally, it is important to handle pentane-1-sulfonyl chloride with caution, as it is a corrosive substance that can cause irritation to the skin, eyes, and respiratory system upon exposure.
Check Digit Verification of cas no
The CAS Registry Mumber 6303-18-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,0 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6303-18:
(6*6)+(5*3)+(4*0)+(3*3)+(2*1)+(1*8)=70
70 % 10 = 0
So 6303-18-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H11ClO2S/c1-2-3-4-5-9(6,7)8/h2-5H2,1H3
6303-18-0Relevant articles and documents
Breslow et al.
, p. 2273 (1969)
N-Sulfonyl homoserine lactones as antagonists of bacterial quorum sensing
Castang, Sandra,Chantegrel, Bernard,Deshayes, Christian,Dolmazon, René,Gouet, Patrice,Haser, Richard,Reverchon, Sylvie,Nasser, William,Hugouvieux-Cotte-Pattat, Nicole,Doutheau, Alain
, p. 5145 - 5149 (2007/10/03)
A series of 11 N-sulfonyl homoserine lactones has been synthesised. Some of them were found to competitively inhibit the action of 3-oxohexanoyl-L- homoserine lactone, the natural inducer of bioluminescence in the bacterium Vibrio fischeri. Molecular modeling suggests a possible explanation based on the prevention of structural rearrangements necessary for the formation of the active dimer of LuxR.
COMPOUNDS AND METHODS FOR CONTROLLING BACTERIAL VIRULENCE
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Page 25, (2010/02/04)
Novel sulfonated homoserine lactones formula I have been found to act ac quorum sensing inhibitors. As such, they may be useful in the treatment of bacterial infections.
