632-15-5

Usage

Uses

3,4-Dimethylthiophene is used in dry onion preparation for seasoning.

Synthesis Reference(s)

The Journal of Organic Chemistry, 27, p. 869, 1962 DOI: 10.1021/jo01050a043

InChI:InChI=1/C6H8S/c1-5-3-7-4-6(5)2/h3-4H,1-2H3

Upstream product

• 632-16-6 2,3-dimethylthiophene 
• 71169-54-5 Spiro 
• 71169-48-7 Spiro 
• 76390-44-8 Spiro 
• 68597-16-0 3',6'-Dihydro-4',5'-dimethylspiro(fluoren-9,2'-<6,6-D₂>-<2H>thiopyran)-1'-oxid 
• 37044-85-2 Spiro 
• 35977-63-0 3',6'-Dihydro-4',5'-dimetylspiro(fluoren-9,2'-<2H>thiopyran)-1'-oxid 
• 35977-66-3 Spiro 
• 188290-36-0 thiophene 
• 624-92-0 Dimethyldisulphide 
• 3141-26-2 3,4-dibromothiophene 
• 77-78-1 dimethyl sulfate 
• 23838-23-5 1,2-di-((E)-prop-1-en-1-yl)disulfane 
• 23838-22-4 (Z,Z)-bis-(1-propenyl) disulfide 

Downstream Products

• 343268-79-1 3,4-dimethylthiophene-2-carbaldehyde 
• 74707-05-4 2,5-dibromo-3,4-dimethylthiophene 
• 89639-74-7 3,4-dimethyl-thiophene-2-carboxylic acid 
• 188290-36-0 thiophene 
• 554-14-3 2-Methylthiophene 
• 638-00-6 2,4-dimethylthiophene 
• 108-88-3 toluene 
• 632-16-6 2,3-dimethylthiophene 
• 638-02-8 2,5-DIMETHYLTHIOPHENE 
• 616-44-4 3-Methylthiophene 
• 71-43-2 benzene 
• 33922-75-7 3,4-dimethyl-2(5H)-thiophenone 
• 583855-47-4 3,4-dimethyl-2-phenylthiophene 
• 169328-87-4 2-bromo-3,4-dimethylthiophene 

Relevant academic research and scientific papers

Catalytic Synthesis of Methylthiophenes

The gas-phase reaction of dimethyl disulfide with thiophene over Co/HZSM-5 catalyst in a helium medium under atmospheric pressure at 250–350°C gave a mixture of mono-, di-, tri-, and tetramethylthiophenes with an overall selectivity of 94–96%.

Synthesis and structure of novel disulfide(trisulfide)-containing thiophenes

A novel trisulfide-containing thiophene, 1,5-dihydrothieno[3,4-e][1,2,3] trithiepine (5), and a disulfide analogue, 1,4-dihydrothieno[3,4-d][1,2]dithiine (4), were designed and synthesized. All the compounds were characterized by FT-IR, NMR, Raman, MS, an

Onion essential oil chemistry. cis- and trans-2-mercapto-3,4-dimethyl-2,3-dihydrothiophene from pyrolysis of bis(1-propenyl) disulfide

Heating the onion oil component bis (1-propenyl) disulfide gives cis- and trans-2-mercapto-3,4-dimethyl-2,3-dihydrothiophene which can lose H2S upon further heating giving 3,4-dimethylthiophene. A dithio-Claisen rearrangement is proposed for the key step.

Reactions of Thiophene and Alkylthiophenes in Glow Discharge

The glow discharge reaction of thiophene is shown to produce thioketene and carbon monosulfide along with other gaseous products.The dominant liquid product is ethynylthiophene.Methylthiophenes and especially dimethylthiophenes produce benzene as one of the major liquid products.

Organosulfur Compounds, L. - 2H-Thiopyrans and Dihydro-2H-thiopyrans, Synthons for Thiophenes

2H-Thiopyran derivatives yield thiophenes on pyrolysis at 240-260 deg C.The influence of substitution in positions 3 to 6 of the 2H-thiopyrans on these new thermal rearrangement and fragmentation reactions is dealt with, and some proposed mechanisms are discussed in detail.A novel three-step synthesis of thiophenes from carbonyl compounds via the corresponding thiones, their -cycloaddition with 1,3-dienes with formation of dihydro-2H-thiopyrans and subsequent thermal conversion is described.In this reaction sequence, whose scope and limitations are outlined, t he thiocarbonyl compound contributes the sulfur and the 1,3-diene the carbon skeleton of the desired thiophenes.