65245-10-5Relevant articles and documents
Direct aldol reactions of glyoxylic acid monohydrate with ketones
Loh, Teck-Peng,Wei, Lin-Li,Feng, Li-Chun
, p. 1059 - 1060 (1999)
The direct aldol reaction of various ketones with glyoxylic acid afforded the β-hydroxy carbonyl compounds in good yields and high regioselectivities.
InCl3-Catalyzed direct aldol reactions of glyoxylic acid monohydrate and glyoxylates with various ketones: Scope and limitations
Loh, Teck-Peng,Feng, Li-Chun,Wei, Lin-Li
, p. 4231 - 4236 (2007/10/03)
The direct aldol reactions of various ketones with glyoxylic acid and glyoxylates afforded the α-hydroxy acid and α-hydroxy esters in good yields and high regioselectivities.
Clay montmorillonite K10 catalyzed aldol-type reaction of aldehydes with silyl enol ethers in water
Loh, Teck-Peng,Li, Xu-Ran
, p. 10789 - 10802 (2007/10/03)
An environmentally friendly method for the cross aldol reaction of silyl enol ethers and ketene silyl acetal with various aldehydes using montmorillonite K10 is described. Cheap and commercially available montmorillonite K10 can be used without the need of an ion exchange process under solvent-free conditions or in water. Hydrate of aldehydes such as glyoxylic acid can be used directly. Thermal treatment of K10 increased the catalytic activity. The catalytic activity was supposed due to the properties of the structure of K10 and its inherent Bronsted acidity.