65350-60-9

Upstream product

• 137325-91-8 (Z)-styrylsulfonyl acetic acid 
• 100-52-7 benzaldehyde 
• 1015692-34-8 diisopropyl (diisopropoxyphosphorylmethylsulfonylmethyl)phosphonate 
• 122-78-1 phenylacetaldehyde 
• 622-24-2 2-phenylethyl chloride 
• 137524-38-0 2-(phenylethylsulfonyl)acetic acid 
• 99186-25-1 NSC₁₅₈₃₆₂ 
• 100-42-5 styrene 
• 52147-97-4 trans 2-phenylethenesulfonyl chloride 
• 68667-91-4 (E)-2-chloro-2-phenylethyl styryl sulfone 
• 80223-52-5 bis-diethylphosphorylmethyl sulphone 
• 68667-98-1 (E)-1-(β-Phenylethylsulfonyl)-2-phenyl-ethen 
• 123-45-5 sulfonyldiacetic acid 

Downstream Products

• 59466-58-9 3r,4ξ,5c-triphenyl-[1,4]thiaphosphinane 1,1-dioxide 
• 135228-18-1 3,5-Diphenyl-4-methyltetrahydro-1,4-thiazine 1,1-Dioxide 
• 886-65-7 trans,trans-1,4-Diphenyl-1,3-butadiene 
• 135228-19-2 2,6-Diphenyl-1,4-dithiane 4,4-Dioxide 
• 1246658-37-6 C₁₈H₁₅NO₂S 
• 97132-66-6 (E)-5--1,5-diphenyl-3-thia-1-penten-3,3-dioxid 
• 59466-59-0 4ξ-methyl-3r,5c-diphenyl-[1,4]thiaphosphinane 1,1-dioxide 
• 59466-66-9 4,4-dimethyl-1,1-dioxo-3r,5c-diphenyl-1-λ⁶-[1,4]thiaphosphinanium; iodide 
• 59466-64-7 4-methyl-3r,5c-diphenyl-[1,4]thiaphosphinane 1,1,4ξ-trioxide 

Relevant academic research and scientific papers

Gram-scale synthesis of β-sulfonyl styrenes

A simple and gram-scale synthesis of β-sulfonyl styrenes has been developed starting from one-pot PPA (polyphosphoric acid)-catalyzed 1,1-diacetoxylation of arylacetaldehydes (ArCH2CHO) with acetic anhydride (Ac2O) followed by deacetoxylative sulfonylation of the resulting 1,1-diacetate intermediate with sodium sulfinates (RSO2Na) in good yields under solvent-free conditions.

Vinyl sulfones

Four neutral vinyl sulfones, two of which are paired with phosphonate groups, are described. The compounds are diisopropyl (2-phenyl-ethenylsulfonyl- meth-yl)phosphonate, C15H23O5PS, (I), diisopropyl {[2-(7-meth-oxy-1,3-benzodi- oxol-5-yl)ethenylsulfon-yl

A novel and convenient synthesis of E,E-bis(styryl)sulfones and E,E-1,4-diaryl-1,3-butadienes

The condensation of 2-phenylethanesulfonylacetic acid (4) with araldehydes (5) in presence of a base gave E-styryl-2-phenylethyl sulfones (6) which on dehydrogenation with DDQ (7) yielded E,E-bis-(styryl)sulfones (8). The 8 on treatment with dichlorotris(triphenyl-phosphine)ruthehium(II) catalyst resulted 1,4-diaryl-1,3-butadienes (9). The configurations of 6, 8 and 9 have been determined based on IR and 1H NMR spectral data.

Reaction of Alkenesulfonyl Chlorides with Olefins Catalyzed by a Ruthenium(II) Complex. A Novel Method for Synthesis of (E,E)-1,4-Diaryl-1,3-butadienes

In the presence of a catalytic amount of dichlorotris(triphenylphosphine)ruthenium(II) (1), alkenesulfonyl chloride (2) was found to react with vinylarenes to give 1:1 adducts (3) in high yield under mild conditions.Dehydrochlorination from the adducts 3 to afford divinyl sulfones (4) takes place by raising the reaction temperature from 80 to 130 deg C.Upon further reaction at 150 deg C, (E,E)-1,4-diaryl-1,3-butadienes (5) are formed in high yield if both of the alkenyl substituents of the sulfonyl chloride and the alkene have aryl groups.The time course of the reaction indicates that the addition of 2 to vinylarenes giving 1:1 adducts 3, dehydrochlorination from the adducts 3 giving divinyl sulfones 4, and desulfonylation from the divinyl sulfone 4 giving 1,3-butadienes 5 proceed successively.The usefulness of the reaction for the syntheses of (E,E)-1,4-diaryl-1,3-butadiene is described.On the other hand, 2 reacts with alkyl olefins in the presence of 1 to give 1:1 adducts (12) with extrusion of sulfur dioxide.

Synthesis of distyryl sulphides, sulphoxides and sulphones by Horner-Wittig reaction in two-phase system

A convenient method is described for the formation of distyryl sulphides, sulphoxides and sulphones.Thus, Horner-Wittig reaction in two-phase system of the corresponding phosphonates with aromatic aldehydes affords the desired α, β unsaturated sulphur com