68667-98-1Relevant academic research and scientific papers
Synthesis of arylethyl (E)-styrylsulfones and arylsulfones by one-pot DIBAL-H/NaH-mediated reaction of β-ketosulfones
Chang, Meng-Yang,Chen, Yi-Chia,Chan, Chieh-Kai
, p. 1739 - 1744 (2014/08/05)
A facile one-pot synthetic route for preparing a series of arylethyl (E)-styrylsulfones or arylethyl arylsulfones is developed. The efficient one-pot DIBAL-H/NaH-mediated route includes reduction of α-benzyl-β- arylketosulfones and retroaldol/aldol or retro aldol reaction of the resulting intermediate. The DIBAL-H/NaH-mediated reaction mechanism has been discussed. Georg Thieme Verlag Stuttgart. New York.
A novel and convenient synthesis of E,E-bis(styryl)sulfones and E,E-1,4-diaryl-1,3-butadienes
Ramana Reddy,Manjubhashini,Reddy,Ramana Reddy,Bhaskar Reddy
, p. 1589 - 1596 (2007/10/02)
The condensation of 2-phenylethanesulfonylacetic acid (4) with araldehydes (5) in presence of a base gave E-styryl-2-phenylethyl sulfones (6) which on dehydrogenation with DDQ (7) yielded E,E-bis-(styryl)sulfones (8). The 8 on treatment with dichlorotris(triphenyl-phosphine)ruthehium(II) catalyst resulted 1,4-diaryl-1,3-butadienes (9). The configurations of 6, 8 and 9 have been determined based on IR and 1H NMR spectral data.
