6639-43-6 Usage
Description
Triphenylacetonitrile, with the chemical formula C20H15N, is a nitrile derivative of triphenylmethane. It is a colorless to light yellow solid that is insoluble in water but soluble in organic solvents. triphenylacetonitrile has a strong, sweet, floral odor and is widely used as a building block in organic synthesis.
Uses
Used in Pharmaceutical Industry:
Triphenylacetonitrile is used as a building block for the production of pharmaceuticals. It serves as a precursor in the synthesis of various pharmaceutical intermediates, contributing to the development of new drugs and medications.
Used in Dye Industry:
In the dye industry, triphenylacetonitrile is utilized as a starting material for the synthesis of dyes. Its unique chemical structure allows for the creation of a wide range of dyes with different properties and applications.
Used in Organic Chemical Synthesis:
Triphenylacetonitrile is used as a precursor in the synthesis of various organic compounds. Its versatile chemical properties make it a valuable component in the production of a broad spectrum of organic chemicals, including pesticides and other specialty chemicals.
Used in Research and Development:
Due to its reactivity and potential for forming a variety of compounds, triphenylacetonitrile is also used in research and development for exploring new chemical reactions and synthesizing novel compounds with potential applications in various industries.
Precautions:
It is important to handle and use triphenylacetonitrile with proper precautions due to its potential health hazards, such as skin and eye irritation. Appropriate safety measures should be taken to minimize exposure and ensure the well-being of individuals working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 6639-43-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,3 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6639-43:
(6*6)+(5*6)+(4*3)+(3*9)+(2*4)+(1*3)=116
116 % 10 = 6
So 6639-43-6 is a valid CAS Registry Number.
6639-43-6Relevant articles and documents
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Budde,Potempa
, p. 258 (1952)
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I2/Li2CO3-promoted cyanation of diarylalcohols through a dual activation process
Hu, Liangzhen,Hussain, Muhammad Ijaz,Deng, Qingfu,Liu, Qing,Feng, Yangyang,Zhang, Xiaohui,Xiong, Yan
supporting information, p. 308 - 314 (2018/12/11)
One-step base promoted strategy for cyanation of α,α-diaryl alcohols has been developed under mild and transition metal-free conditions. This method provides a straightforward and facile way towards the synthesis of β,γ-unsaturated nitriles and α-phenylnitiriles from α-vinyl carbinols and α,α-diaryl methanols, respectively, up to 99% yield. Moreover, various azides and ethers could also be accessed from their respective nucleophiles under standard reaction conditions.
Hydride Reduction by a Sodium Hydride-Iodide Composite
Too, Pei Chui,Chan, Guo Hao,Tnay, Ya Lin,Hirao, Hajime,Chiba, Shunsuke
supporting information, p. 3719 - 3723 (2016/03/26)
Sodium hydride (NaH) is widely used as a Br?nsted base in chemical synthesis and reacts with various Br?nsted acids, whereas it rarely behaves as a reducing reagent through delivery of the hydride to polar π electrophiles. This study presents a series of reduction reactions of nitriles, amides, and imines as enabled by NaH in the presence of LiI or NaI. This remarkably simple protocol endows NaH with unprecedented and unique hydride-donor chemical reactivity.
Efficient assembly of α-aryl and α-vinyl nitriles via iron-catalyzed ether bond activation
Fan, Xiaohui,Guo, Kun,Guan, Yong-Hong,Fu, Lin-An,Cui, Xiao-Meng,Lv, Hao,Zhu, Hong-Bo
supporting information, p. 1068 - 1071 (2014/02/14)
A novel and practical method for the synthesis of diverse α-aryl and α-vinyl nitriles was developed via an iron-catalyzed sp3 C-O ether bond cleavage with C-C bond formation in the reaction of π-activated ethers with TMSCN.