68595-19-7

Basic information

• Product Name: 5-oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carbonitrile
• Synonyms: 5-oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carbonitrile;5-OXO-1-(TOLUENE-4-SULFONYL)-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE-4-CARBONITRILE
• CAS NO: 68595-19-7
• Molecular Formula: C₁₈H₁₆N₂O₃S
• Molecular Weight: 340.39624
• Mol File: 68595-19-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 153-154 °C
• Boiling Point: 564.5±60.0 °C(Predicted)
• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 5-oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carbonitrile(68595-19-7)
• EPA Substance Registry System: 5-oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carbonitrile(68595-19-7)

Safety Data

• Hazardous Substances Data: 68595-19-7(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 134-20-3 2-carbomethoxyaniline 
• 50998-74-8 methyl N-tosylanthranilate 
• 105895-93-0 methyl 2-{(3-cyanopropyl)[(4-methylphenyl)sulfonyl]amino}benzoate 

Downstream Products

• 169879-06-5 4-bromo-1-(4-nitrobenzoyl)-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one 
• 168626-71-9 2-methyl-6-(4-nitrobenzoyl)-1,4,5,6-tetrahydroimidazo-[4,5-d][1]benzazepine 
• 168626-93-5 4'-(2-methyl-5,6-dihydro-4H-oxazolo[4,5-d][1]benzoazepine-6-carbonyl)-2-phenylbenzanilide 
• 1127-74-8 1,2,3,4-tetrahydro-5H-benzo[b] azepin-5-one 
• 717917-14-1 2-methyl-6-[(4-methylphenyl)sulfonyl]-1,4,5,6-tetrahydroimidazo[4,5-d][1]benzazepine 
• 195531-22-7 {4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}amine 
• 318237-73-9 2-methyl-1,4,5,6-tetrahydroimidazo[4,5-d][1]benzazepine 
• 168626-94-6 conivaptan hydrochloride 
• 29489-04-1 4-bromo-1-[(4-methylphenyl)sulfonyl]-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one 

Relevant articles and documents

A new synthetic route to YM087, an arginine vasopressin antagonist

A new synthesis of N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl} biphenyl-2-carboxamide monohydrochloride (1, YM087) via new imidazobenzazepine intermediates is described. This method remarkably improves the overall yiel