68692-74-0

Basic information

• Product Name: Benzoic acid, 2-(1-propenyl)-, (Z)-
• CAS NO: 68692-74-0
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Mol File: 68692-74-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(1-propenyl)-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(1-propenyl)-, (Z)-(68692-74-0)
• EPA Substance Registry System: Benzoic acid, 2-(1-propenyl)-, (Z)-(68692-74-0)

Safety Data

• Hazardous Substances Data: 68692-74-0(Hazardous Substances Data)

Upstream product

• 93-55-0 1-phenyl-propan-1-one 
• 103441-58-3 1-(2-iodophenyl)propan-1-one 
• 144-62-7 oxalic acid 
• 1530-32-1 ethyltriphenylphosphonium bromide 
• 119-67-5 o-carboxybenzaldehyde 
• 88-65-3 2-bromobenzoic-acid 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 124-38-9 carbon dioxide 
• 70913-21-2 (E)-1-bromo-2-(2-methylethenyl)benzene 
• 16859-59-9 3-hydroxy-1(3H)-isobenzofuranone 
• 34599-72-9 methyl 2-(prop-1-en-1-yl)benzoate 
• 127-08-2 potassium acetate 
• 925-90-6 ethylmagnesium bromide 
• 610-97-9 o-iodo-methyl-benzoic acid 

Downstream Products

• 1351766-10-3 2-p-tolyl-3-vinylisoindolin-1-one 
• 1351766-13-6 2-(3,4-dimethylphenyl)-3-vinylisoindolin-1-one 
• 1351766-15-8 2-(3,4-dimethylphenyl)-3-methylisoquinolin-1(2H)-one 
• 1351766-17-0 2-(2,4-dimethylphenyl)-3-vinylisoindolin-1-one 
• 1351766-19-2 2-(2,4-dimethylphenyl)-3-methylisoquinolin-1(2H)-one 
• 1351766-21-6 2-(4-chlorophenyl)-3-vinylisoindolin-1-one 
• 1351766-23-8 2-(4-chlorophenyl)-3-methylisoquinolin-1(2H)-one 
• 32346-23-9 (Z)-3-ethylidene-2-phenylisoindolin-1-one 
• 32346-24-0 (E)-3-ethylidene-2-phenylisoindolin-1-one 
• 1351765-45-1 (E)-N-phenyl-2-(prop-1-enyl)benzamide 
• 1351765-58-6 (E)-2-(prop-1-enyl)-N-p-tolylbenzamide 
• 1351765-60-0 (E)-N-(3,4-dimethylphenyl)-2-(prop-1-enyl)benzamide 
• 1351765-62-2 (E)-N-(2,4-dimethylphenyl)-2-(prop-1-enyl)benzamide 
• 1351765-64-4 (E)-N-(4-chlorophenyl)-2-(prop-1-enyl)benzamide 

Relevant articles and documents

Palladium-catalyzed: Ortho -halogen-induced deoxygenative approach of alkyl aryl ketones to 2-vinylbenzoic acids

The 2-vinylbenzoic acids have wide applications in the field of polymer chemistry and are key precursors for the synthesis of important bioactive molecules. Herein, an ortho-halogen-induced deoxygenative approach for the generation of 2-vinylbenzoic acids from alkyl aryl ketones by palladium catalysis is discovered and explored. This approach requires no base or stoichiometric additives and can be carried out through a simple one-step process. Furthermore, the present reaction is scalable up to one-gram scale. The commercially available palladium on carbon (5 wt%) was used as a heterogeneous catalyst and showed excellent recyclability (5 times) without significant loss in catalytic activity. Pleasingly, under our optimized conditions, the alpha alkyl substituted 2-iodoacetophenones exhibit good diastereoselectivity and predominantly (E)-2-vinylbenzoic acids were obtained with good to excellent yields.

Synthesis of Secondary Unsaturated Lactams via an Aza-Heck Reaction

The preparation of unsaturated secondary lactams via the palladium-catalyzed cyclization of O-phenyl hydroxamates onto a pendent alkene is reported. This method provides rapid access to a broad range of lactams that are widely useful building blocks in alkaloid synthesis. Mechanistic studies support an aza-Heck-type pathway.

Supramolecular control of selectivity in hydroformylation of vinyl arenes: Easy access to valuable β-aldehyde intermediates

Go against the flow! A rationally designed regioselective hydroformylation catalyst, [Rh/L], in which noncovalent ligand-substrate interactions allow the unprecedented reversal of selectivity from the typical α-aldehyde to the otherwise unfavored product β-aldehyde, is reported. This catalytic system opens up novel and sustainable synthetic pathways to important intermediates for the fine-chemicals industry.