68968-13-8

Basic information

• Product Name: 2-(3-chlorophenyl)-1-(4-methoxyphenyl)ethanone
• Synonyms: 2-(3-chlorophenyl)-1-(4-methoxyphenyl)ethanone
• CAS NO: 68968-13-8
• Molecular Weight: 260.72
• Mol File: 68968-13-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(3-chlorophenyl)-1-(4-methoxyphenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-chlorophenyl)-1-(4-methoxyphenyl)ethanone(68968-13-8)
• EPA Substance Registry System: 2-(3-chlorophenyl)-1-(4-methoxyphenyl)ethanone(68968-13-8)

Safety Data

• Hazardous Substances Data: 68968-13-8(Hazardous Substances Data)

Upstream product

• 528892-46-8 1-chloro-3-[2-(4-methoxyphenyl)ethynyl]benzene 
• 696-62-8 para-iodoanisole 
• 766-83-6 m-chlorophenylacetylene 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 587-04-2 m-Chlorobenzaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 144664-10-8 3-chloro-mandelic acid-amide 
• 620-20-2 1-Chloro-3-chloromethyl-benzene 
• 7647-01-0 hydrogenchloride 
• 54551-87-0 3'-chloro-4-methoxy-benzoin 
• 7758-99-8 copper(II) sulfate 
• 3424-93-9 4-methoxyphenylacetamide 
• 100-66-3 methoxybenzene 
• 41904-39-6 3-chloro-benzeneacetyl chloride 

Downstream Products

• 7465-87-4 N-benzyl-4-methoxybenzamide 
• 153529-22-7 3'-chloro-4-methoxy-bibenzyl-α-ol 

Relevant articles and documents

2,2-Diazido-1,2-diarylethanones: Synthesis and Reactivity with Primary Amines

We describe the synthesis and reactivity of a new class of diazidated compounds: the 2,2-diazido-1,2-diarylethanones. The diazides are easily accessible from 1,2-diarylethanones through a mild and simple protocol for the direct oxidative diazidation, using iodine and sodium azide in DMSO at room temperature. In studies towards their reactivity with amine nucleophiles under basic conditions, the diazides are shown to undergo a controlled fragmentation reaction that provides a straightforward access to the corresponding amides. In stark contrast to our previous results on the amine-triggered fragmentation of diazidated compounds, aromatic nitriles are found to be by-products of synthetic value. The net reaction consisting of diazidation and subsequent fragmentation, thus, provides a simple way to convert 1,2-diarylethanones into both aromatic amides and nitriles.

Antifungal agents. 5. Chloro and amino derivatives of 1,2-diaryl-1-(1H-imidazol-1-yl)ethane with potent antifungal activities

Various derivatives of 1,2-diaryl-1-(1H-imidazol-1-yl)ethane have been synthesized and tested against Candida albicans and Candida spp.In vitro essays showed chloro and amino derivatives to be as active as miconazole and bifonazole and more potent than ketoconazole.Structure-activity relationships of the new imidazole antifungal agents are discussed.antifungal agents/estrogen-like imidazoles/1,2-diaryl-1-(1H-imidazol-1-yl)ethane derivatives