68968-13-8

Upstream product

• 100-66-3 methoxybenzene 
• 41904-39-6 3-chloro-benzeneacetyl chloride 
• 528892-46-8 1-chloro-3-[2-(4-methoxyphenyl)ethynyl]benzene 
• 696-62-8 para-iodoanisole 
• 766-83-6 m-chlorophenylacetylene 
• 123-11-5 4-methoxy-benzaldehyde 
• 144664-10-8 3-chloro-mandelic acid-amide 
• 620-20-2 1-Chloro-3-chloromethyl-benzene 
• 7647-01-0 hydrogenchloride 
• 54551-87-0 3'-chloro-4-methoxy-benzoin 
• 7758-99-8 copper(II) sulfate 
• 3424-93-9 4-methoxyphenylacetamide 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 587-04-2 m-Chlorobenzaldehyde 

Downstream Products

• 7465-87-4 N-benzyl-4-methoxybenzamide 
• 153529-22-7 3'-chloro-4-methoxy-bibenzyl-α-ol 

Relevant academic research and scientific papers

2,2-Diazido-1,2-diarylethanones: Synthesis and Reactivity with Primary Amines

We describe the synthesis and reactivity of a new class of diazidated compounds: the 2,2-diazido-1,2-diarylethanones. The diazides are easily accessible from 1,2-diarylethanones through a mild and simple protocol for the direct oxidative diazidation, using iodine and sodium azide in DMSO at room temperature. In studies towards their reactivity with amine nucleophiles under basic conditions, the diazides are shown to undergo a controlled fragmentation reaction that provides a straightforward access to the corresponding amides. In stark contrast to our previous results on the amine-triggered fragmentation of diazidated compounds, aromatic nitriles are found to be by-products of synthetic value. The net reaction consisting of diazidation and subsequent fragmentation, thus, provides a simple way to convert 1,2-diarylethanones into both aromatic amides and nitriles.

Nickel catalysed electrosynthesis of ketones from organic halides and iron pentacarbonyl. Part 2: Unsymmetrical ketones

Unsymmetrical aryl-benzyl or aryl-alkyl ketones are obtained by electrolysing in an undivided cell a DMF solution containing two organic halides, iron pentacarbonyl and a catalytic amount of a nickel-2,2′-bipyridine complex.

Antifungal agents. 5. Chloro and amino derivatives of 1,2-diaryl-1-(1H-imidazol-1-yl)ethane with potent antifungal activities

Various derivatives of 1,2-diaryl-1-(1H-imidazol-1-yl)ethane have been synthesized and tested against Candida albicans and Candida spp.In vitro essays showed chloro and amino derivatives to be as active as miconazole and bifonazole and more potent than ketoconazole.Structure-activity relationships of the new imidazole antifungal agents are discussed.antifungal agents/estrogen-like imidazoles/1,2-diaryl-1-(1H-imidazol-1-yl)ethane derivatives