6938-38-1

Basic information

• Product Name: Benzoic acid, 4-Methoxy-, 1-Methylethyl ester
• Synonyms: Benzoic acid, 4-Methoxy-, 1-Methylethyl ester
• CAS NO: 6938-38-1
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.22706
• Mol File: 6938-38-1.mol
• Article Data: 47

Chemical Properties

• Boiling Point: 375.2°C at 760 mmHg
• Flash Point: 180.7°C
• Appearance: /
• Density: 1.636g/cm³
• Vapor Pressure: 3.65E-06mmHg at 25°C
• Refractive Index: 1.693
• CAS DataBase Reference: Benzoic acid, 4-Methoxy-, 1-Methylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-Methoxy-, 1-Methylethyl ester(6938-38-1)
• EPA Substance Registry System: Benzoic acid, 4-Methoxy-, 1-Methylethyl ester(6938-38-1)

Safety Data

• Hazardous Substances Data: 6938-38-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H7Cl4NO2/c14-7-3-1-2-6(4-7)13(20)18-9-5-8(15)12(19)11(17)10(9)16/h1-5,19H,(H,18,20)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 67-63-0 isopropyl alcohol 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 5419-55-6 Triisopropyl borate 
• 201230-82-2 carbon monoxide 
• 6310-14-1 4-methoxyacetophenone hydrazone 
• 213596-33-9 2-(4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborolane 
• 4181-97-9 phenyl 4-methoxybenzoate 
• 15226-74-1 dicobalt octacarbonyl 
• 696-62-8 para-iodoanisole 
• 13939-06-5 molybdenum hexacarbonyl 
• 100-09-4 4-methoxybenzoic acid 
• 75-26-3 isopropyl bromide 
• 443682-79-9 5,5-dimethyl-3-(p-methoxyphenyl)-1,4,2-dioxazole 

Downstream Products

• 123-11-5 4-methoxy-benzaldehyde 
• 877627-79-7 3-chloromethyl-4-methoxy-benzoic acid isopropyl ester 
• 1392227-40-5 (E)-iso-propyl 2-(3-ethoxy-3-oxoprop-1-en-1-yl)-4-methoxybenzoate 
• 1392227-39-2 (E)-iso-propyl 2-(3-n-butoxy-3-oxoprop-1-en-1-yl)-4-methoxybenzoate 

Relevant articles and documents

Transition-Metal-Free DMAP-Mediated Aromatic Esterification of Amides with Organoboronic Acids

A new, transition-metal-free, effective method for aromatic esterification of amides with organoboronic acids has been developed. A wide range of benzoate derivatives were obtained with yields ranging from moderate to good. The catalytic reaction shows a broad substrate scope and excellent functional group tolerance. Conceptually, DMAP mediates the reaction and is crucial for this transformation.

Mechanochemical Palladium-Catalyzed Carbonylative Reactions Using Mo(CO)6

Esters and amides were mechanochemically prepared by palladium-catalyzed carbonylative reactions of aryl iodides by using molybdenum hexacarbonyl as a convenient solid carbonyl source and avoiding a direct handling of gaseous carbon monoxide. Real-time monitoring of the mechanochemical reaction by in situ pressure sensing revealed that CO is rapidly transferred from Mo(CO)6 to the active catalytic system without significant release of molecular carbon monoxide.

Nickel-Catalyzed Esterification of Amides Under Mild Conditions

Abstract: The use of ligands to adjust the catalytic activity of the catalyst for esterification of amides is challenge in organic chemistry. In this paper, Nickel(II)-NHC-catalyzed the esterification reaction between N,N-di-Boc amide and alcohols at room temperature have been demonstrated. The imidazolium salt bearing a hydroxyl functionalized side arm showed high effective catalytic activity in the activation of the amide N–C bond in air atmosphere. Graphic Abstract: [Figure not available: see fulltext.].