7315-17-5

Basic information

• Product Name: 3-(2-CHLOROPHENYL)PROPIONITRILE
• Synonyms: 3-(2-CHLOROPHENYL)PROPIONITRILE;2-CHLOROHYDROCINNAMONITRILE;Benzenepropanenitrile, 2-chloro-;2-Chlorohydrocinnamonitrile 99%
• CAS NO: 7315-17-5
• Molecular Formula: C₉H₈ClN
• Molecular Weight: 165.62
• Mol File: 7315-17-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 83 °C0.15 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.139 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.539(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-(2-CHLOROPHENYL)PROPIONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-CHLOROPHENYL)PROPIONITRILE(7315-17-5)
• EPA Substance Registry System: 3-(2-CHLOROPHENYL)PROPIONITRILE(7315-17-5)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-37/39
• RIDADR: 3276
• WGK Germany: 3
• HazardClass: IRRITANT, IRRITANT-HARMFUL
• Hazardous Substances Data: 7315-17-5(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

Uses

2-Chlorohydrocinnamonitrile was used as analytical standard for the GC-MS detection of 2-chlorobenzylidenemalononitrile (CS riot control agent).

General Description

2-Chlorohydrocinnamonitrile is the thermal degradation product of 2-chlorobenzylidenemalononitrile (CS riot control agent).

Upstream product

• 134306-93-7 3-(2-chlorophenyl)propionamide 
• 542-76-7 3-Chloropropionitrile 
• 108-90-7 chlorobenzene 
• 1005-06-7 2-chlorophenylethyl chloride 
• 143-33-9 sodium cyanide 
• 14650-19-2 2-(o-chlorobenzyl)cyanoacetic acid 
• 141692-07-1 α-benzenesulfonyl-2-chloro-ξ-cinnamonitrile 
• 89-98-5 2-chloro-benzaldehyde 
• 105-34-0 methyl 2-cyanoacetate 
• 105-56-6 ethyl 2-cyanoacetate 
• 7677-24-9 trimethylsilyl cyanide 
• 17849-38-6 2-Chlorobenzyl alcohol 
• 75-05-8 acetonitrile 
• 74738-21-9 3-(2'-chlorophenyl)-2-propenenitrile 

Downstream Products

• 1643-28-3 3-(2-chlorophenyl)propanoic acid 
• 18655-48-6 3-(2-chlorophenyl)propan-1-amine 
• 1473-47-8 Benzocyclobuten-1-carbonsaeure-chlorid 
• 15100-35-3 Bicyclo<4.2.0>octa-1,3,5-triene-7-methanol 
• 6809-95-6 1-Bicyclo[4.2.0]octa-1,3,5-trien-7-yl-2-phenyl-ethanone 
• 6813-94-1 Bicyclo[4.2.0]octa-1,3,5-trien-7-yl-cyclohexyl-methanone 
• 7315-27-7 1-Bicyclo[4.2.0]octa-1,3,5-trien-7-yl-ethanone O-butyl-oxime 

Relevant articles and documents

Dihydroxy pyrimidine compound and use thereof

The invention provides a dihydroxy pyrimidine compound, its structural general formula is: Wherein R1 In order to contain the substituent of the aryl, heterocyclic or containing substituent is C1 - C6 alkyl; R2 Is C1 - C6 alkyl, C1 - C6 alkyl aryl, C1 - C6 alkyl heterocyclic group or a hydrogen atom; x, y each is between 0 - 6 is any natural number. The invention also provides a two-hydroxy pyrimidine compounds in the preparation of anti-influenza virus in the application. The present invention provides a dihydroxy pyrimidine compounds to the influenza virus activity has better inhibition, can remarkably reduce the toxicity of the influenza virus, and cytotoxicity is relatively low, thus can such compounds for the preparation of anti-influenza virus drugs.

Formal reductive addition of acetonitrile to aldehydes and ketones

An efficient and highly productive rhodium-catalyzed method for the synthesis of nitriles employing aldehydes or ketones, methyl cyanoacetate, water and carbon monoxide as starting materials has been developed. Simple rhodium chloride without any ligands can be used. The fine tuning of the substrate can lead to the activity higher than 5000 TON.

Monoalkylation of acetonitrile by primary alcohols catalyzed by iridium complexes

The monoalkylation of acetonitrile by primary alcohols was achieved in a one-pot sequence in the presence of iridium catalysts. A diversity of nitriles has been obtained from aryl- and alkyl-methanols in excellent yield.