7334-51-2Relevant articles and documents
Neutral complexes of first row transition metals bearing unbound thiocyanates and their assembly on metallic surfaces
Ciszek, Jacob W.,Keane, Zachary K.,Cheng, Long,Stewart, Michael P.,Yu, Lam H.,Natelson, Douglas,Tour, James M.
, p. 3179 - 3189 (2006)
A series of transition metal coordination complexes designed to assemble on gold surfaces was synthesized, their electronic structure and transitions analyzed, and their magnetic properties studied. By taking advantage of recently developed thiocyanate assembly protocols, these molecules were then assembled onto a gold surface, without the need for an inert atmosphere, to give a loosely packed monolayer. The assembled molecules exhibit properties similar to that of the bulk molecules, indicating little change in molecular structure outside of chemisorption.
A fulvene route to group 4 metallocene complexes bearing 4,7-bis(dimethylamino)-substituted indenyl ligands
Sierra, Jesus Cano,Kehr, Sierra Gerald,Froehlich, Roland,Erker, Gerhard
, p. 2260 - 2265 (2004)
N,N,N′,N′-Tetramethylsuccinamide (15) was selectively converted into the functionalized aminofulvene 16. Subsequent treatment with reagent 17, [ZrCl2(NMe2)2(L)2] (L = THF or 0.5 DME), resulted in the formation of the cyclization product 4,7- bis(dimethylamino)indene (21). Deprotonation with n-butyllithium, followed by the reaction of the resulting substituted indenyllithium reagent 22 with ZrCl4, gave the metallocene [4,7-bis(dimethylamino)indenyl] 2ZrCl2 (23). The reaction of 22 with ZrCl3Cp furnished the complex [4,7-bis(dimethylamino)indenyl]CpZrCl2 (24). Fulvene 16, as well as the metallocene dichlorides 23 and 24, were characterized by X-ray diffraction. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
Copper-catalyzed homodimerization of nitronates and enolates under an oxygen atmosphere
Do, Hien-Quang,Tran-Vu, Hung,Daugulis, Olafs
, p. 7816 - 7818 (2013/01/16)
A method for copper-catalyzed oxidative dimerization of nitronates and enolates using oxygen as the terminal oxidant has been developed. Cyclization through oxidative intramolecular coupling is also feasible for both nitronates and enolates. The mild reaction conditions lead to good functional group tolerance.
Synthesis and antitumor activity of 2,5-bis(3′-indolyl)-furans and 3,5-bis(3′-indolyl)-isoxazoles, nortopsentin analogues
Diana, Patrizia,Carbone, Anna,Barraja, Paola,Kelter, Gerhard,Fiebig, Heinz-Herbert,Cirrincione, Girolamo
experimental part, p. 4524 - 4529 (2010/08/22)
A series of novel 2,5-bis(3′-indolyl)furans and 3,5-bis(3′-indolyl)isoxazoles were synthesized as antitumor agents. The antiproliferative activity was evaluated in vitro toward diverse human tumor cell lines. Initially 5 isoxazoles and 3 furan derivatives were tested against a panel of 10 human tumor cell lines and the most active derivatives 3c and 4a were selected to be evaluated in an extended panel of 29 cell lines. By exhibiting mean IC50 values of 17.4 μg/mL (3a) and 20.5 μg/mL (4c), in particular 4c showed a high level of tumor selectivity toward the 29 cell lines.