7626-68-8Relevant academic research and scientific papers
NBS/DMSO-mediated synthesis of (2,3-dihydrobenzo[b] [1,4]oxathiin-3-yl)methanols from aryloxymethylthiiranes
Dong, Jun,Xu, Jiaxi
, p. 9037 - 9044 (2018/06/08)
(2,3-Dihydrobenzo[b][1,4]oxathiin-3-yl)methanols were synthesized via reactions of aryloxymethylthiiranes and N-bromosuccinimide (NBS) in DMSO under microwave irradiation. The reaction mechanism was proposed as an intramolecular aromatic electrophilic substitution of 1-bromo-2-(aryloxymethyl)thiiran-1-iums, generated from aryloxymethylthiiranes and NBS, and the subsequent DMSO nucleophilic ring opening reaction of thiiran-1-iums followed by the water displacement. The current method provides a direct and simple strategy in the efficient preparation of (2,3-dihydrobenzo[b][1,4]oxathiin-3-yl)methanols from readily available aryloxymethylthiiranes.
Novel route to N-alkyl- and N,N′-dialkylhydrazines by high-pressure alkylation of azines
Agafonov,Dudin,Preobrazhenskii
, p. 714 - 716 (2007/10/03)
Reactions of alkyl halides with azines of p-nitrobenzaldehyde, benzaldehyde, and p-methoxybenzaldehyde at a high pressure (10 kbar) were studied. Hydrolysis of the reaction mixtures gives pure N-monoalkyl- or N,N′-dialkylhydrazines in high yields, depending on the structure of the starting azine and the solvent nature. It was found that non-symmetrical N,N′-dialkylhydrazines can be synthesized without isolating intermediate N-monoquaternary immonium salts. The effect of the phase transition of the solvent on the direction of the alkylation is discussed.
Platinum carbonyl derived catalysts on inorganic and organic supports: A comparative study
Paul, Himadri,Basu, Susmit,Bhaduri, Sumit,Lahiri, Goutam Kumar
, p. 309 - 316 (2007/10/03)
Fumed silica, silica gel, silica-alumina and cross-linked (5.5%) polystyrene have been functionalized with quaternary ammonium groups and the Chini cluster [Pt12(CO)24]2- has been anchored onto these functionalized materials by ion pairing. A catalyst has also been prepared by the adsorption of Na2[Pt12(CO)24] on unfunctionalized fumed silica. The catalytic activities of the resultant materials, and that of commercially purchased 5% platinum on alumina have been studied for the hydrogenation of a variety of unsaturated compounds. The substrates studied are: α-acetamidocinnamic acid, cyclohexanone, acetophenone, methyl pyruvate, ethyl acetoacetate, nitrobenzene and benzonitrile. Compared to the polystyrene supported catalyst, the inorganic oxide supported catalysts have higher surface areas and for most of the substrates have notably higher activities. The functionalized fumed silica-based catalyst gives higher conversions than functionalized silica gel and silica-alumina- based catalysts. In the hydrogenation of acetophenone and ethyl acetoacetate, the functionalized fumed silica-based catalyst show superior activity compared to the commercial platinum catalyst, and the catalyst made by conventional adsorption method. In benzonitrile hydrogenation with all the cluster-derived catalysts a hydrazine derivative is selectively formed, but when the commercial platinum catalyst is used benzyl amine is the main product.
Selective Reduction of Imines with the Diborane-Methanol System
Nose, Atsuko,Kudo, Tadahiro
, p. 4817 - 4820 (2007/10/02)
The selective reduction of imines with diborane-methanol system was investigated.This system reduced imines quatitatively, and other functional groups tested were unaffected.Keywords-imine; diborane; selective reduction; diborane-methanol system; secondary amine; dimethoxyborane
