76475-12-2

Upstream product

• 802294-64-0 propionic acid 
• 110-83-8 cyclohexene 
• 79-31-2 isobutyric Acid 
• 127-65-1 chloroamine-T 
• 7080-50-4 chloramine T trihydrate 
• 68820-12-2 cyclohexyl-N-tosyl aziridine 
• 64-19-7 acetic acid 
• 75-77-4 chloro-trimethyl-silane 
• 58107-40-7 trans-2-(N-tosylamino)-1-cyclohexanol 

Downstream Products

• 68820-12-2 cyclohexyl-N-tosyl aziridine 

Relevant academic research and scientific papers

Highly efficient regioselective ring openings of N-tosylaziridines to haloamines using ferric (III) halides

FeX3 (X = Cl, Br) were found to be very effective reagents and powerful catalysts for regioselective ring openings of a variety of N-tosylaziridines with them to afford the corresponding β-haloamines in good to excellent yields with high regios

TBD-catalyzed ring opening of aziridines with silylated nucleophiles

The ring opening of N-tosylaziridines with silylated nucleophiles catalyzed by 1,5,7-triazabicyclo[4,4,0]dec-5-ene (TBD) afforded the corresponding- functionalized sulfonamides in excellent yields under mild reaction conditions. Copyright

An efficient method for opening N -tosylaziridines with silylated nucleophiles by using polystyrene-supported 1,5,7-triazabicyclo[44.0]dec-5-ene as a reusable organocatalyst

Polystyrene-supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene (PS-TBD) catalyzes the ring opening of N-tosylaziridines with trimethylsilyl cyanide, trimethylsilyl azide, or trimethylsilyl halides to give the corresponding products in high yields. PS-TBD can b

Polystyrene-supported TBD catalyzed ring-opening of N-tosylaziridines with silylated nucleophiles

Polystyrene-supported TBD (PS-TBD) catalyzes the ring-opening of N-tosylaziridines with silylated nucleophiles to give the corresponding products in high yields. PS-TBD was easily recovered and reused without significant loss of catalytic activity.

Hydrated nickel (II) halides mediated ring opening reaction with N-tosylaziridines

An efficient and water tolerant method for the synthesis of β-haloamines is described utilizing hydrated nickel (II) halides (NiX 2·nH2O X = Cl, Br, I) and aziridines as starting materials. N-Tosylaziridines reacted with NiCl2/

SN2-type ring opening of substituted-N-tosylaziridines with zinc (II) halides: Control of racemization by quaternary ammonium salt

Quaternary ammonium salt mediated highly regioselective ring opening of aziridines with zinc(II) halides to racemic and non-racemic β-halo amines in excellent yield and selectivity is described. The reaction proceeds via an SN2-type pathway and

BF3·OEt2-Mediated highly regioselective S N2-type ring-opening of N-activated aziridines and N-activated azetidines by tetraalkylammonium halides

(Chemical Equation Presented) A highly regioselective Lewis acid-mediated SN2-type ring-opening of N-sulfonylaziridines and azetidines with tetraalkylammonium halides in CH2Cl2 solution to afford 1,2- and 1,3-haloamines in excellent yields is described. An easy diastereoselective route toward substituted chiral N-tosylaziridines has been developed. The mechanism of ring-opening via SN2 pathway has been confirmed by the formation of chiral haloamines with excellent er and dr. Chloroamines obtained from 2,3-disubstituted aziridines were converted to the chiral N-tosylamines via radical dehalogenation. 2009 American Chemical Society.

TTMPP: An efficient organocatalyst in the ring-opening of aziridines with silylated nucleophiles

The ring-opening of N-tosylaziridines with silylated nucleophiles catalyzed by tris(2,4,6-trimethoxyphenyl)phosphine (TTMPP) afforded the corresponding β-functionalized sulfonamides in excellent yield under mild reaction conditions.

PPh3/halogenating agent-mediated highly efficient ring opening of activated and non-activated aziridines

We report here the use of PPh3/halogenating agents as highly efficient reagents for the ring opening of aziridines with halides. The method works effectively for both activated and non-activated aziridines, and furnishes the products in excelle

Efficient copper-catalyzed benzylic amidation with anhydrous chloramine-T

Benzylic hydrocarbons are selectively converted to the corresponding sulfonamides by the [Cu(CH3CN)4]PF6-catalyzed reaction with anhydrous TolSO2NNaCl (chloramine-T). Under the same conditions, representative ethers are also α-amidated; olefins produce allyl sulfonamides, aziridines, and/or β-chloro sulfonamides.