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Usage

Uses

Used in Pharmaceutical Industry:
6-methyl-1,2,4-benzenetriol is used as a pharmaceutical ingredient for its antioxidant properties, which can help in the development of drugs targeting various health conditions. Its antioxidant nature may contribute to the prevention of oxidative stress-related diseases.
Used in Cosmetic Industry:
In the cosmetic industry, 6-methyl-1,2,4-benzenetriol is used as an active ingredient in skincare products for its antioxidant and potentially anti-aging effects. Its ability to neutralize free radicals may help in maintaining skin health and reducing signs of aging.
Used in Food Industry:
6-methyl-1,2,4-benzenetriol is used as a food additive for its antioxidant properties, which can help in preserving the freshness and quality of food products. It may also contribute to the prevention of oxidation-related spoilage and extend the shelf life of certain food items.
Used in Chemical Research:
In the field of chemical research, 6-methyl-1,2,4-benzenetriol is used as a research compound for studying its chemical properties, reactivity, and potential applications in various chemical processes. Its unique structure and properties make it an interesting subject for scientific investigation.
Used in Environmental Applications:
6-methyl-1,2,4-benzenetriol can be used in environmental applications, such as in the development of eco-friendly cleaning products or as a component in pollution control technologies. Its antioxidant properties may help in reducing the environmental impact of certain pollutants.

InChI:InChI=1/C7H8O3/c1-4-2-5(8)3-6(9)7(4)10/h2-3,8-10H,1H3

Upstream product

• 487-69-4 2,4-dihydroxy-6-methylbenzaldehyde 
• 504-15-4 orcinol 
• 2446-75-5 2-hydroxy-6-methyl-[1,4]benzoquinone 
• 38790-14-6 1,2,5-trimethoxy-3-methylbenzene 
• 36776-43-9 (((5-methyl-1,3-phenylene)bis(oxy))bis(methylene))dibenzene 
• 2896-67-5 2-methyl-6-methoxyphenol 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 611-68-7 2-methoxy-6-methyl-1,4-benzoquinone 
• 28814-66-6 2-methyl-6-methoxybenzene-1,4-diol 
• 7732-18-5 water 
• 623-11-0 1-methyl-4-nitrosobenzene 
• 7722-84-1 dihydrogen peroxide 
• 286364-90-7 2,4-Dibenzyloxy-1-hydroxy-6-methylbenzene 
• 39803-51-5 2,4-bis-(benzyloxy)-6-methylbenzaldehyde 

Downstream Products

• 3790-88-3 4,2',4'-trihydroxy-6,6'-dimethyl-biphenyl-2,5-dione 
• 2446-75-5 2-hydroxy-6-methyl-[1,4]benzoquinone 
• 128-68-7 phoenicin 
• 70265-69-9 6,7-dihydroxy-2,2,5-trimethyl-4-chromanone 
• 3790-89-4 4,4'-dihydroxy-2,2'-dimethyl-[1,1']bicyclohexa-1,4-dienyl-3,6,3',6'-tetraone 
• 176181-82-1 echinotinctone 
• 16275-95-9 2,3,6-trihydroxy-p-toluic acid methyl ester 
• 27613-31-6 2,4,5-trihydroxy-6-methylbenzoic acid 
• 857000-89-6 3,4,6-triacetoxy-2-methyl-benzaldehyde 
• 19104-05-3 3,4,6-trihydroxy-2-methyl-benzoic acid methyl ester 
• 194221-93-7 3,4,6-trihydroxy-2-methyl-benzaldehyde 

Relevant academic research and scientific papers

Synthesis of Echinotinctone, A Fungal Fluorone Pigment

Echinotinctone (3) is formed by acid-catalyzed condensation of 1,2,4-trihydroxytoluene (1) with orcylaldehyde (2), a reaction mimicking the probable biosynthesis. A more efficient stepwise synthesis proceeds via the benzophenone intermediate 11, which can be converted to 2,6-dihydroxy-1,8-dimethyl-3H-xanthenn-3-one (3) by LiAlH4 reduction and subsequent acid-catalyzed ring closure.

DNA cleavage by Di- and trihydroxyalkylbenzenes. Characterization of products and the roles of O2, Cu(II), and alkali

Several 5-alkyl-1,3-dihydroxybenzene (5-alkylresorcinol, 1) and 6-alkyl-1,2,4-trihydroxybenzene (2) derivatives were prepared and used to study the mechanism by which such compounds effect Cu(II)-dependent DNA strand scission. Comparison of the methyl, n-pentyl, n-undecyl, and n-hexadecyl derivatives in each structural series indicated that the efficiency of DNA cleavage increased with increasing length of the alkyl substituent. DNA cleavage by the 5-alkylresorcinols appears to involve initial oxygenation of the benzene nucleus, a process that occurs readily at alkaline pH in the presence of Cu2+ and O2. The resulting trihydroxylated benzenes mediate DNA cleavage in a reaction dependent on the presence of both Cu2+ and O2. The mechanism appears to involve reduction of Cu2+ by the trihydroxybenzene moiety in 2, with subsequent formation of reactive oxygen species. The ability of catalase and dimethyl sulfoxide to suppress DNA strand scission is consistent with the intermediacy of H2O2 and ?OH in the DNA strand scission process.

NOVEL AND SELECTIVE SYNTHESES OF NEW ANALOGUES OF PRECOCENE-2 AND PRECOCENE-3 CONTAINING 5-METHYL- OR 8-METYL-SUBSTITUENTS

New analogues of precocene-2 and precocene-3 containing 5-methyl- or 8-methyl-substituents have been synthesised in good yields utilising regioselective O-alkylation of 6,7-dihydroxy-2,2,5-trimethyl-4-chromanone and 6,7-dihydroxy-2,2,8-trimethyl-4-chromanone as the key step.