7786-64-3

Upstream product

• 67-56-1 methanol 
• 71-23-8 propan-1-ol 
• 89-82-7 pulegone 
• 64-17-5 ethanol 
• 100400-22-4 1-hydroxy-2-isopropyl-5-methyl-cyclohexanecarbonitrile 
• 2385-77-5 (R)-Citronellal 
• 28745-06-4 3-methyl-6-isopropyl-2-oxymethylenecyclohexanone 
• 89-78-1 menthol 
• 2216-51-5 (-)-menthol 
• 89-83-8 thymol 
• 89-81-6 piperitone 
• 2216-52-6 Neomenthol 
• 10458-14-7 (2R,5S)-menthone 
• 13368-65-5 (3R)-3-methylcyclohexanone 

Downstream Products

• 872266-49-4 (3-hydroxy-p-menthan-3-yl)-acetic acid 
• 38618-20-1 1-Allyl-2-isopropyl-5-methyl-cyclohexanol 
• 18368-90-6 2-Isopropyl-5-methyl-1-phenyl-cyclohexanol 
• 22339-24-8 1-methyl-4-isopropyl-2-(3'-oxobutyl)-cyclohexan-3-one 
• 33651-16-0 2-isopropyl-5-methyl-1-phenylethynyl-cyclohexanol 
• 162551-92-0 3-isopropyl-6-methyl-2-oxo-cyclohexanecarboxylic acid 
• 619-52-3 (1R)-menth-3-ene 
• 26127-89-9 ((1S,2R,5S)-1-Hydroxy-2-isopropyl-5-methyl-cyclohexyl)-acetic acid tert-butyl ester 
• 50281-16-8 (1R,4S)-1-isopropyl-4-methyl-2-methylenecyclohexane 
• 100400-22-4 1-hydroxy-2-isopropyl-5-methyl-cyclohexanecarbonitrile 
• 18427-47-9 2,6-Dibromo-2-isopropyl-5-methylcyclohexanone 
• 83462-16-2 2-acetoxymenthone 

Relevant academic research and scientific papers

Origin of High Diastereoselectivity in Reactions of Seven-Membered-Ring Enolates

Unlike many reactions of their six-membered-ring counterparts, the reactions of chiral seven-membered-ring enolates are highly diastereoselective. Diastereoselectivity was observed for a range of substrates, including lactam, lactone, and cyclic ketone derivatives. The stereoselectivity arises from torsional and steric interactions that develop when electrophiles approach the diastereotopic π-faces of the enolates, which are distinguished by subtle differences in the orientation of nearby atoms of the ring.

A Mild, General, Metal-Free Method for Desulfurization of Thiols and Disulfides Induced by Visible-Light

A visible-light-induced metal-free desulfurization method for thiols and disulfides has been explored. This radical desulfurization features mild conditions, robustness, and excellent functionality compatibility. It was successfully applied not only to the desulfurization of small molecules, but also to peptides.

Catalytic study of the copper-based magnetic nanocatalyst on the aerobic oxidation of alcohols in water

A copper-based magnetic nanocatalyst has been prepared by co-precipitation method and characterized by FESEM, EDS, TEM, XRD, XRF, ICP–OES, FTIR, and BET analysis. This new nanocatalyst displays a good activity toward the aerobic oxidation of a wide range of alcohols in water. Moreover, it is recyclable up to five following runs by simple filtration without any significant loss of its catalytic activity.

SBA-15 Supported 1-Methyl-2-azaadamanane N-Oxyl (1-Me-AZADO) as Recyclable Catalyst for Oxidation of Alcohol

Herein, we designed and synthesized an SBA-15 supported 1-methyl-2-azaadamanane N-oxyl (1-Me-AZADO) and investigated its catalytic performance for selective oxidation of alcohols under Anelli's conditions. The first example of immobilization of 1-Me-AZADO was very important to advance the oxgenation effectively because this supported N-oxyl has excellent catalytic activity for oxidation of alcohols to carbonyl compounds, and more importantly, it can be conveniently recovered and reused at least 6 times without significant effect on its catalytic efficiency.

A TEMPO-Functionalized Ordered Mesoporous Polymer as a Highly Active and Reusable Organocatalyst

The properties of high stability, periodic porosity, and tunable nature of ordered mesoporous polymers make these materials ideal catalytic nanoreactors. However, their application in organocatalysis has been rarely explored. We report herein for the first time the incorporation of a versatile organocatalyst, 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO), into the pores of an FDU-type mesoporous polymer via a pore surface engineering strategy. The resulting FDU-15-TEMPO possesses a highly ordered mesoporous organic framework and enhanced stability, and shows excellent catalytic activity in the selective oxidation of alcohols and aerobic oxidative synthesis of 2-substituted benzoxazoles, benzimidazoles and benzothiazoles. Moreover, the catalyst can be easily recovered and reused for up to 7 consecutive cycles.

Selective C-C Bond Cleavage of Cycloalkanones by NaNO2/HCl

A novel selective fragmentation of cycloalkanones by NaNO2/HCl has been established. The C-C bond cleavage reaction proceeds smoothly under mild conditions, selectively affording versatile keto acids or oxime acids. The methodology can streamline the synthesis of valuable chiral molecules and isocoumarins from readily available feedstocks.

Rapid, chemoselective and mild oxidation protocol for alcohols and ethers with recyclable N-chloro-N-(phenylsulfonyl)benzenesulfonamide

Chlorine is the 20th most abundant element on the earth compared to bromine, iodine, and fluorine, a sulfonimide reagent, N-chloro-N-(phenylsulfonyl)benzenesulfonamide (NCBSI) was identified as a mild and selective oxidant. Without activation, the reagent was proved to oxidize primary and secondary alcohols as well as their symmetrical and mixed ethers to corresponding aldehydes and ketones. With recoverable PS-TEMPO catalyst, selective oxidation over chlorination of primary and secondary alcohols and their ethers with electron-donating substituents was achieved. The reagent precursor of NCBSI was recovered quantitatively and can be reused for synthesizing NCBSI.

Synthesis of enantiopure triols from racemic Baylis?Hillman adducts using a diastereoselective peroxidation reaction

Using a chiral (?)-menthone auxiliary, enantiopure cyclic derivatives of Baylis?Hillman adducts were synthesized. A diastereoselective peroxidation reaction was used to introduce an oxygen atom and establish another stereocenter. The resulting products could be elaborated by employing a one-flask reduction?acetylation protocol followed by a diastereoselective nucleophilic substitution reaction. Removal of the (?)-menthone auxiliary provided an enantiopure triol with a structure related to naturally occurring polyols.

Photochemical Transformations with Iodine Azide after Release from an Ion-Exchange Resin

This report discloses the photochemical homolytic cleavage of iodine azide after its formation following release from polymer-bound bisazido iodate(I) anions. A series of radical reactions are reported including the 1,2-functionlization of alkenes and the unprecedented chemoselective oxidation of secondary alcohols in the presence of primary alcohols.