7790-01-4 Usage
Uses
Used in Chemical Synthesis:
1,1-Dicyanoethyl Acetate is used as a selective N-acetylation agent for the modification of nitrogen-containing compounds. Its selectivity allows for the targeted acetylation of specific nitrogen atoms in complex molecules, which is crucial for the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,1-Dicyanoethyl Acetate is used as a selective N-acetylation agent for the synthesis of drug candidates and active pharmaceutical ingredients (APIs). The selective acetylation of nitrogen atoms can improve the stability, solubility, and bioavailability of drug molecules, leading to enhanced therapeutic effects and reduced side effects.
Used in Agrochemical Industry:
1,1-Dicyanoethyl Acetate is also utilized in the agrochemical industry as a selective N-acetylation agent for the synthesis of pesticides and other crop protection agents. The selective acetylation can help in the development of more effective and environmentally friendly agrochemicals by improving their target specificity and reducing non-specific interactions with non-target organisms.
Used in Research and Development:
In research and development, 1,1-Dicyanoethyl Acetate is employed as a selective N-acetylation agent for the study of nitrogen-containing compounds and their properties. This selective acetylation can provide valuable insights into the structure-activity relationships of various nitrogen-containing molecules, aiding in the design and optimization of new compounds with desired properties.
Check Digit Verification of cas no
The CAS Registry Mumber 7790-01-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,9 and 0 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7790-01:
(6*7)+(5*7)+(4*9)+(3*0)+(2*0)+(1*1)=114
114 % 10 = 4
So 7790-01-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N2O2/c1-5(9)10-6(2,3-7)4-8/h1-2H3
7790-01-4Relevant academic research and scientific papers
Ortho Amides, XLVI. - Contributions to the Chemistry of Bis(dialkylamino)malononitriles
Kantlehner, Willi,Greiner, Ulrich
, p. 965 - 973 (2007/10/02)
The reaction of chloroformamidinium chlorides 2 with sodium cyanide in the two-phase system ether/water affords bis(dialkylamino)malononitriles 3 with good yields.From 3a and morpholine or aniline the guanidines 5 and 6 can be obtained, respectively.Alcohol-free sodium ethoxide transforms 3a into the urea acetal 10b, whereas in the reaction of 3a with alkoxides in alcohol ortho carbamic esters 11a, b are produced.The malonic esters and acetoacetic esters 12 react with 3a in the presence of two equivalents of sodium hydride to give the ketene aminals 13.The reactionof 3a with malononitrile furnishes the guanidinium salt 14, which cyclized by hydrogen chloride to the pyridinetricarbonitrile 15.In the presence of sodium hydride, 3a and malononitrile or cyanoacetic esters 17 from the ketene aminal 16 and the 1,2,3-tricyanopropenides 18a-c, respectively.The analogous salts 20 and 21 result from the reaction of 3a with the barbituric acid derivatives 19a, and b, respectively.Hydrogen chloride reacts in ether with 3a to afford the piperazinetetracarbonitrile 22.Reaction of carboxylic acid chlorides yields the cyanoformamidinium salt 28a; byproducts are acyl cyanides 29 and dimeric acyl cyanides 30.Triethyloxonium tetrafluoroborate transforms 3a into the salt 28b.Bromine and iodine react with 3a to produce the salts 28c, d and 28e, f, respectively, depending on the stoichiometric ratios of the starting materials.The thiocyanate 28g is prepared from sulfur and 3a.
TRIBUTYLTIN CYANIDE: A FACILE CYANATING AGENT OF ACYL CHLORIDES
Tanaka, Masato
, p. 2959 - 2962 (2007/10/02)
Tributyltin cyanide was prepared from tributyltin chloride and potassium cyanide, and was found to be an efficient cyanation reagent for acyl chlorides to give acyl cyanides in excellent yields.
