79309-63-0Relevant academic research and scientific papers
Steroid Derived Mesoionic Gold and Silver Mono- and Polymetallic Carbenes
Frutos, María,De La Torre, María C.,Sierra, Miguel A.
, p. 11174 - 11185 (2015/12/17)
A two-step synthesis of gold mesoionic carbene complexes containing estrone moieties has been developed. The method uses the methylation of the triazole nucleus, followed by the treatment of the triazolium salt with Ag2O and transmetalation wit
Gold(i) "click" 1,2,3-triazolylidenes: Synthesis, self-assembly and catalysis
Kilpin, Kelly J.,Paul, Ursula S. D.,Lee, Ai-Lan,Crowley, James D.
supporting information; experimental part, p. 328 - 330 (2011/03/17)
Novel gold(i) "click" carbene(1,2,3-triazolylidene) complexes have been synthesised, characterised and exploited for the self-assembly of a metallomacrocycle and as precatalysts for gold(i)-catalysed reactions.
Bronsted acid catalyzed formal insertion of isocyanides into a C-O bond of acetals
Tobisu, Mamoru,Kitajima, Aki,Yoshioka, Sachiko,Hyodo, Isao,Oshita, Masayuki,Chatani, Naoto
, p. 11431 - 11437 (2008/03/13)
The Bronsted acid catalyzed formal insertion of an isocyanide into a C-O bond of an acetal is described. A diverse array of acyclic and cyclic acetals can be applied to the catalytic insertion to form α-alkoxy imidates. Functional groups, such as nitro, c
Deacylative oxidation strategy for the preparation of α- functionalized carbonyls
Brodsky, Benjamin H.,Du Bois
, p. 2619 - 2621 (2007/10/03)
(Matrix Presented) α-Alkoxylation and amination of carbonyl derivatives is made possible through a unique deacylative coupling reaction that proceeds via in situ Rh-carbene formation and subsequent heteroatom-H (X-H) insertion. Reactions perform optimally
Asymmetric rhodium carbene insertion into the Si-H bond: Identification of new dirhodium(II) carboxylate catalysts using parallel synthesis techniques
Buck, Richard T.,Coe, Diane M.,Drysdale, Martin J.,Ferris, Leigh,Haigh, David,Moody, Christopher J.,Pearson, Neil D.,Sanghera, J. Bobby
, p. 791 - 816 (2007/10/03)
Decomposition of methyl 2-diazophenylacetate in the presence of silanes and a chiral dirhodium(II) catalyst results in Si-H insertion of the intermediate carbenoid with varying degrees of enantioselectivity. New chiral dirhodium(II) carboxylate catalysts were identified using solution phase parallel synthesis techniques.
A facile one-pot synthesis of α-hydroxy acids and their derivatives
Florac,Le Grel,Baudy-Floc'h,Robert
, p. 741 - 743 (2007/10/02)
2-Substituted oxirane-1,1-dicarbonitriles react with water, alcohols or phenol to give 2-substituted 2-hydroxyacetic acids, alkyl-2-alkoxyacetates and phenyl 2-phenoxyacetates, respectively. Reaction of 2-substituted oxirane-1,1-dicarbonitrile with thiophenol and a nucleophile, typically water ethanol or urea, gave 2-(phenylthio)acetic acids, ethyl 2-(phenylthio)acetates and N-aminocarbonyl-2-(phenylthio)acetamides.
Mechanism of Formation of Natural Cyclopropanes: Synthesis of Postulated Intermediates in Presqualene and Chrysanthemyl Alcohol Biosynthesis
Boulton, Keith,Shirley, Ian,Smith, Ian H.,Whiting, Donald A.
, p. 1817 - 1824 (2007/10/02)
The α-unsaturated esters (15), (28), and (33) have been used in deconjugative additions to ketones, to provide the β,γ-hydroxy esters (17), (18), (29), (30), and (37) and hence the unsaturated diols (22), (23), and (38).These diols have been postulated as precursors to the natural cyclopropanes chrysanthemyl alcohol and presqualene, through homoallylic participation.Experiments with cell-free extract of Artemisia annua foliage show that neither diol (22) nor (23) is converted to chrysanthemyl alcohol.Limited experiments with an homogenate of Rhizopus arrhizus provide little support for the intervention of the diol (38) in squalene biosynthesis.
NUCLEOPHILIC ADDITION TO STYRYL SULPHONES. PART I. A STUDY ON THE REGIOCHEMISTRY.
Benedetti, F.,Fabrissin, S.,Risaliti, A.
, p. 3887 - 3894 (2007/10/02)
Styryl sulphones undergo nucleophilic addition, with the nucleophile adding at the α- or the β-position, with respect to the sulphone group; β-attack is normally favoured over α-attack.Factors which can change the regioselectivity in favour of the addition of the nucleophile to the α-position are discussed for heteronucleophiles as well as carbon nucleophiles.
