79813-33-5

Upstream product

• 79813-32-4 (+/-)-di-O-methylsequirin D 
• 79754-54-4 7-hydroxy-4-p-hydroxybenzyl-1,2,3,4-tetrahydro-1-naphthol 
• 120-44-5 1,4-di(4-methoxyphenyl)ethanone 
• 67295-38-9 1, 2-bis(4-methoxyphenyl)prop-2-en-1-one 
• 6443-74-9 p-methoxy-α-p-methoxyphenylcinnamonitrile 
• 20498-71-9 1,2-bis(4-methoxyphenyl)ethan-1-ol 
• 67295-37-8 3,4-bis-p-methoxyphenylbutanoic acid 
• 79754-49-7 3-hydroxy-3,4-bis-(4-methoxy-phenyl)-butyric acid ethyl ester 
• 123-11-5 4-methoxy-benzaldehyde 
• 79754-53-3 p-methoxy-α-p-methoxyphenylcinnamaldehyde 
• 79754-50-0 ethyl 2-ethoxycarbonyl-4,5-bis-p-methoxyphenyl-5-oxopentanoate 
• 79754-47-5 4,5-bis(4-methoxyphenyl)-5-oxopentanenitrile 
• 79754-48-6 4,5-bis-(p-methoxyphenyl)pentanoic acid 
• 79754-51-1 4,5-bis-p-methoxyphenyl-5-oxopentanoic acid 

Relevant academic research and scientific papers

Synthesis of 5-p-Hydroxybenzyl-5,6-dihydro-2-naphthol, (+/-)-Sequirin D

A high-yield six-step synthesis of sequirin D (1a), a naturally occurring norlignan, is described.Michael addition of deoxyanisoin (2) to acrylonitrile gives a ketonitrile (3), which on Wolff-Kishner reduction is reduced and hydrolysed in situ to 4,5-bis-