80070-91-3

Upstream product

• 536-74-3 phenylacetylene 
• 106-40-1 4-bromo-aniline 
• 26456-05-3 10-methylacridinium perchlorate 
• 100-42-5 styrene 
• 98-86-2 acetophenone 
• 20102-12-9 2-hydroxy-2-phenylpropionitrile 
• 81512-11-0 2-(N-4-bromophenylamino)-2-phenylpropanenitrile 

Downstream Products

• 1075181-22-4 N-4-bromophenyl-N-[(1-phenyl)ethyl]amine 
• 913830-00-9 (R)-N-(4-bromophenyl)-1-phenylethylamine 
• 330793-63-0 N‐(1‐phenylethyl)‐4‐bromoaniline 
• 330793-63-0 (+)-N-(4-bromophenyl )-1-phenylethylamine 
• 330793-63-0 (-)-N-(4-bromophenyl )-1-phenylethylamine 
• 898825-98-4 6-bromo-2-phenyl-quinoxaline 
• 330793-63-0 (+)-N-(4-bromophenyl)-1-phenylethylamine 
• 330793-63-0 (-)-N-(4-bromophenyl)-1-phenylethylamine 

Relevant academic research and scientific papers

Syntheses of Triangular Gold Complexes and Their Applications in Hydroamination Reaction

Triangular all-metal complexes have aroused our research interest due to their unique structural and properties. Herein, through the facile reduction of μ3-oxo complex [μ3-O(PPh3Au)3]+BF4s

Synthesis and application of axially chiral biscarbolines with functional N-O and sulfone for 1,2-transfer hydrogenations of ketimines

A series of axially chiral biscarboline-based sulfones were synthesized from L-tryptophane and applied for enantioselective 1,2-transfer hydrogenations of ketimines using trichlorosilane. The catalyst 4e, which had a tertiary butyl group, exhibited a good conversion and high enantioselectivities up to 96%ee in the series of reactions.

An efficient proline-based homogeneous organocatalyst with recyclability

In this work, a homogeneous organocatalyst was developed for the asymmetric reduction of imines. This catalyst could be separated by cyclodextrin-modified Fe3O4@SiO2 magnetic nanoparticles and then released back into a fre

Thiolate-Protected Au 25 (SC 2 H 4 Ph) 18 Nanoclusters as a Catalyst for Intermolecular Hydroamination of Terminal Alkynes

Au 25 (SC 2 H 4 Ph) 18 nanoclusters have high catalytic activity for hydroamination of terminal alkynes. This reaction proceeds under O 2 or air. The presence of molecular oxygen has a profound effect

Neutral and cationic cyclic (alkyl)(amino)carbene mercury [cAAC-Hg(ii)] complexes: Scope of hydroamination of alkynes with organomercury compounds

This study demonstrates the first synthesis of cyclic (alkyl)(amino)carbene (cAAC) adducts of Hg(ii), [cAACMe·HgBr(μ-Br)]2 (1a) and [cAACcy·HgBr(μ-Br)]2 (1b). Adduct 1b catalyzes intermolecular hydroamination of

Palladium-catalyzed aerobic oxidative hydroamination of vinylarenes using anilines: A wacker-type amination pathway

A palladium-catalyzed intermolecular hydroamination of vinylarene derivatives using anilines has been developed for the first time under aerobic conditions, where the regioselective formation of N-arylketimines is accomplished. The current aerobic oxidative hydroamination pathway of anilines is distinct from that of palladiumcatalyzed hydroamination reactions that proceed to give sec-arylethylamine and arylethylamine derivatives, identifying a longstanding missing reaction pathway, Wacker-type amination, to N-arylketimines using anilines. The ready availability of both starting materials, vinylarenes and anilines, offers an attractive and facile synthetic route to N-arylketimines in good to excellent yields.

HΒ Catalyzed Condensation Reaction Between Aromatic Ketones and Anilines: To Access Ketimines (Imines)

Abstract: A simple approach for the formation of imines by condensation of ketones and anilines over heterogeneous catalyst (Hβ zeolite) has been successfully developed. The present catalytic system scope was explored for various aromatic ketones and anil

Magnetically Recoverable N-Heterocyclic Carbene-Gold(I) Catalyst for Hydroamination of Terminal Alkynes

We prepared a magnetically recoverable gold(I) catalyst by immobilizing an N-heterocyclic carbene-gold(I) complex on magnetite and applied it to the hydroamination of alkynes. By employing 2 mol% of the magnetite-supported gold(I) catalyst, the hydroamination of terminal alkynes proceeded smoothly to provide the corresponding imine in a fair chemical yield. Moreover, after the reaction, the magnetic gold(I) catalyst was readily recovered by use of an external magnet and could be reused up to five times.

Copper-Catalyzed Cascade Cycloamination of α-Csp3-H Bond of N-Aryl Ketimines with Azides: Access to Quinoxalines

A copper-catalyzed cycloamination of α-Csp3-H bond of N-aryl ketimines with sodium azide has been developed. This methodology provides an efficient access to quinoxalines and features mild reaction conditions and readily available ketimines with diverse functional group tolerance.

Rh(iii)-catalyzed relay carbenoid functionalization of aromatic C-H bonds: Access to π-conjugated fused heteroarenes

A novel Rh(iii)-catalyzed relay cross-coupling/cyclization cascade between arylketoimines and diazoesters is described. This transformation provides a concise access to unique π-conjugated 1-azaphenalenes (1-APLEs) via a double aryl Csp2-H bond