80174-16-9

Basic information

• Product Name: 1,4-Butanediol, 1-(4-methoxyphenyl)-
• CAS NO: 80174-16-9
• Molecular Formula: C11H16O3
• Molecular Weight: 196.246
• Mol File: 80174-16-9.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1,4-Butanediol, 1-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Butanediol, 1-(4-methoxyphenyl)-(80174-16-9)
• EPA Substance Registry System: 1,4-Butanediol, 1-(4-methoxyphenyl)-(80174-16-9)

Safety Data

• Hazardous Substances Data: 80174-16-9(Hazardous Substances Data)

Upstream product

• 503-30-0 trimethylene oxide 
• 123-11-5 4-methoxy-benzaldehyde 
• 24165-60-4 1-(4-methoxyphenyl)but-3-en-1-ol 
• 100-66-3 methoxybenzene 
• 1443342-50-4 6-(4-methoxyphenyl)-2,2-diphenyl-1,2-oxasilinane 
• 15118-67-9 ethyl 3-(4-methoxybenzoyl)-propionate 
• 3153-44-4 4-(4-methoxy-phenyl)-4-oxo-butyric acid 
• 80173-74-6 [5-(4-Methoxy-phenyl)-furan-2-yl]-carbamic acid benzyl ester 
• 80174-06-7 5-(4-Methoxy-phenyl)-furan-2-carbonyl azide 
• 52938-99-5 5-((4-methoxy)phenyl)furan-2-carboxylic acid 
• 5447-74-5 methyl 3-(4-methoxybenzoyl)propionate 
• 26153-41-3 γ-(4-methoxyphenyl)-γ-butyrolactone 
• 80173-84-8 N-carbobenzyloxy-5-hydroxy-5-p-methoxyphenyl-3-pyrrolin-2-one 

Downstream Products

• 1266606-39-6 1-(4-methoxyphenyl)butane-1,4-diyl diacetate 
• 56047-51-9 4-(4-methoxyphenyl)butyraldehyde 
• 52244-70-9 4-(4-methoxyphenyl)butan-1-ol 
• 594847-89-9 (S)-1-(4’-methoxyphenyl)butan-1,4-diol 
• 594847-91-3 (R)-1-(4’-methoxyphenyl)butan-1,4-diol 
• 126135-42-0 (R)-(+)-γ-(p-Methoxyphenyl)-γ-butyrolactone 
• 128994-28-5 (S)-(-)-γ-(p-Methoxyphenyl)-γ-butyrolactone 
• 594847-83-3 (S)-4-hydroxy-4-(4-methoxyphenyl)butyl acetate 
• 594847-86-6 1-(4-methoxyphenyl)-4-methylcarbonyloxy-(1R)-butyl acetate 
• 79623-15-7 2-p-methoxyphenyltetrahydrofuran 

Relevant articles and documents

Heterocyclization involving benzylic C(sp3)-H functionalization enabled by visible light photoredox catalysis

A general and efficient method for heterocyclization involving benzylic C(sp3)-H functionalization enabled by visible light photoredox catalysis to access a wide range of structurally diverse oxygen as well as nitrogen heterocycles up to a gram scale is reported. The potential application of this new methodology is demonstrated by the total synthesis of (-)-codonopsinine and (+)-centrolobine. Herein it is proposed that selectfluor, unlike a fluorinating reagent, acts as an oxidative quencher and a hydrogen radical acceptor.

A Re2O7catalyzed cycloetherification of monoallylic diols

A Re2O7catalyzed cycloetherification of monoallylic diols is described. The reaction features short reaction time, mild reaction conditions and exclusive E selectivity. A wide range of monoallylic alcohols with alkyl or aryl substituents on olefin smoothly undergo ring closure to deliver corresponding oxa-heterocycles. The reaction is also operationally simple and not sensitive to air and moisture.

Mn-catalyzed three-component reactions of imines/nitriles, grignard reagents, and tetrahydrofuran: An expedient access to 1,5-amino/keto alcohols

An expedient Mn-catalyzed three-component synthesis of 1,5-amino/keto alcohols from Grignard reagents, imines/nitriles, and tetrahydrofuran (THF) is described, which deviates from the classic Grignard addition to imines/nitriles in THF solvent. THF is split and sewn in an unprecedented manner in the reaction, leading to the formation of two geminal C-C bonds via C-H and C-O cleavage. Mechanistic experiments and DFT calculations reveal radical and organo-Mn intermediates in the catalytic cycle and the α-arylative ring-opening of THF as the key reaction step.