80715-09-9

Basic information

• Product Name: Benzene, 1,1'-(1,2-ethenediyl)bis[3,5-dimethoxy-
• Synonyms: (E)-3,3',5,5'-tetramethoxystilbene;3,3',5,5'-tetramethoxy-trans-stilbene;1,2-bis(3,5-dimethoxyphenyl)ethylene;trans-3,3',5,5'-tetramethoxystilbene;(E)-1,2-bis(3,5-dimethoxyphenyl)ethene;trans-3,5,3',5'-tetramethoxystilbene
• CAS NO: 80715-09-9
• Molecular Formula: C18H20O4
• Molecular Weight: 300.354
• Mol File: 80715-09-9.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(1,2-ethenediyl)bis[3,5-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(1,2-ethenediyl)bis[3,5-dimethoxy-(80715-09-9)
• EPA Substance Registry System: Benzene, 1,1'-(1,2-ethenediyl)bis[3,5-dimethoxy-(80715-09-9)

Safety Data

• Hazardous Substances Data: 80715-09-9(Hazardous Substances Data)

Upstream product

• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 24131-30-4 (3,5-dimethoxybenzyl)triphenylphosphonium bromide 
• 877-88-3 3,5-dimethoxybenzyl bromide 
• 108957-75-1 diethyl 3,5-dimethoxybenzylphosphonate 
• 872-85-5 pyridine-4-carbaldehyde 
• 667458-79-9 3,5-dimethoxybenzyl 3,5-bis(trifluoromethyl)phenyl sulfone 
• 98-03-3 thiophene-2-carbaldehyde 
• 498-60-2 furan-3-carboxaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 626-20-0 3-methoxystyrene 
• 40243-87-6 3,5-dimethoxystyrene 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 2628-16-2 p-acetoxystyrene 
• 705-76-0 3,5-dimethoxybenzyl alcohol 

Downstream Products

• 125910-10-3 1,2-bis(3,5-dimethoxyphenyl)ethylene 
• 22976-41-6 3,5,3',5'-tetramethoxy-bibenzyl 
• 1182284-00-9 (E)-2-hydroxy-3,5,3′,5′-tetramethoxystilbene 
• 1325680-21-4 3,6-di(2-pyridyl)-4,5-di(3,5-dimethoxyphenyl)-1,4-dihydropyridazine 
• 1325680-08-7 3,6-di(2-pyridyl)-4,5-di-(3,5-dimethoxyphenyl)pyridazine 
• 80715-11-3 3,5,3',5'-Tetraacetoxydiphenylethan 
• 80715-10-2 1-(3,5-dihydroxyphenyl)-2-(3,5-dihydroxyphenyl)ethane 
• 150258-79-0 (E)-1-<3,5-bis(benzyloxy)phenyl>-2-<3,5-bis(benzyloxy)phenyl>ethene 
• 33626-09-4 (E)-3,3',5,5'-tetrahydroxystilbene 

Relevant articles and documents

Vinyl-Stilbene Compounds and Uses Thereof

The present invention relates to a biphenyl - stilbene (Vinyl-stilbene) - based compound and a pharmaceutical composition for preventing or treating norovirus infection comprising the same as an active ingredient. The present invention can be usefully used as a pharmaceutical composition for treating norovirus infection by showing superior norovirus inhibitory activity and lower cell toxicity as compared to previously known compounds.

Photoinitiated carbonyl-metathesis: Deoxygenative reductive olefination of aromatic aldehydes: Via photoredox catalysis

Carbonyl-carbonyl olefination, known as McMurry reaction, represents a powerful strategy for the construction of olefins. However, catalytic variants that directly couple two carbonyl groups in a single reaction are less explored. Here, we report a photoredox-catalysis that uses B2pin2 as terminal reductant and oxygen trap allowing for deoxygenative olefination of aromatic aldehydes under mild conditions. This strategy provides access to a diverse range of symmetrical and unsymmetrical alkenes with moderate to high yield (up to 83%) and functional-group tolerance. To follow the reaction pathway, a series of experiments were conducted including radical inhibition, deuterium labelling, fluorescence quenching and cyclic voltammetry. Furthermore, NMR studies and DFT calculations were combined to detect and analyze three active intermediates: a cyclic three-membered anionic species, an α-oxyboryl carbanion and a 1,1-benzyldiboronate ester. Based on these results, we propose a mechanism for the CC bond generation involving a sequential radical borylation, "bora-Brook" rearrangement, B2pin2-mediated deoxygenation and a boron-Wittig process.

One-Pot Intermolecular Reductive Cross-Coupling of Deactivated Aldehydes to Unsymmetrically 1,2-Disubstituted Alkenes

The phospha-Peterson reaction between a lithiated secondary phosphane, MesP(Li)TMS, and an aldehyde affords Mes-phosphaalkenes which, upon methanol addition and P-oxidation, react with a second carbonyl compound site specifically to produce unsymmetric alkenes. The E/Z selectivity of the one-pot cross coupling is largely determined by the electronic nature of the aryl substituent of the first aldehyde, with electron-donating groups giving rise to increased amounts of Z-alkenes.