80751-51-5

Usage

Uses

Used in Cleaning and Personal Care Products:
EDTA is utilized as a chelating agent in cleaning and personal care products to enhance their effectiveness. It binds to metal ions, which helps to prevent the formation of insoluble salts that can reduce the cleaning power of these products and improve their stability.
Used in Food Industry:
In the food industry, EDTA is used as a preservative and to maintain the stability of various food products. Its chelating properties help to prevent spoilage and extend the shelf life of foods by binding to metal ions that could otherwise catalyze oxidation reactions.
Used in Medicine:
EDTA serves as a chelating agent in medical applications, primarily for the treatment of heavy metal poisoning. It is capable of binding to various heavy metals, such as lead, mercury, and cadmium, facilitating their safe removal from the body. Additionally, it is used in certain medical imaging procedures to enhance the contrast in X-ray images.
Used in Laboratories:
In laboratory settings, EDTA is employed as a reagent to assist in various chemical reactions. Its ability to bind metal ions is particularly useful in removing these ions from samples, which can interfere with analytical techniques and results, thus ensuring more accurate and reliable analyses.

Upstream product

• 50-00-0 formaldehyd 
• 19522-69-1 N-butylethylenediamine 
• 143-33-9 sodium cyanide 
• 7327-60-8 nitrilotriacetonitrile 
• 79-11-8 chloroacetic acid 
• 56-40-6 glycine 
• 64-69-7 Iodoacetic acid 
• 3926-62-3 sodium monochloroacetic acid 
• 142-73-4 iminodiacetic acid 
• 7664-41-7 ammonia 
• 7732-18-5 water 
• 19247-05-3 N,N-dicarboxymethyl hydrazine 
• 7647-01-0 hydrogenchloride 
• 74-90-8 hydrogen cyanide 

Downstream Products

• 192638-62-3 N,N'-<1,2-phenylenebis>bis 
• 134842-93-6 (Carboxymethyl-phenoxycarbonylmethyl-amino)-acetic acid 
• 64019-57-4 N,N',N''-tris(2-benzimidazolylmethyl)amine 
• 188639-48-7 K⁽¹⁺⁾*Fe⁽³⁺⁾*C₆H₆O₆N^(3-)*C₁₄H₁₀O₂N₂^(2-)*H⁽¹⁺⁾=K[Fe(C₆H₆O₆N)(C₁₄H₁₁O₂N₂)] 
• 188639-44-3 K⁽¹⁺⁾*Fe⁽³⁺⁾*C₆H₆O₆N^(3-)*C₇H₅O₂N^(2-)*H⁽¹⁺⁾=K[Fe(C₆H₆O₆N)(C₇H₆O₂N)] 

Relevant academic research and scientific papers

PROCESS TO PREPARE A CHELATING AGENT OR PRECURSOR THEREOF USING A CYANIDE SALT

The present invention relates to a process comprising the reaction of a cyanide with an amino acid and an aldehyde, characterized in that the cyanide is a cyanide salt, the amino acid is aspartic acid and/or glutamic acid in the acidic form, and the process is performed under acidic pH by the addition of between 0 and 1 equivalent of an acid based on the amount of aspartic or glutamic acid.

Substrate and method for producing the substrate

To enable measurements having high S/N ratios, by suppressing non specific adsorption. A substrate that includes: a base material; and chelators which are three dimensionally covalently bound to the base material at a density of 7.8×1015/mm3 or greater and 4.5×1017/mm3 or less, or two dimensionally covalently bound to the base material at a planar density of 2.0×1011/mm2 or greater and 1.0×1013/mm2 or less, is used. Metal ions are coordinately bound to the chelators, and a bioactive substance having histidine tags are coordinately bound to the metal ions. A blocking agent having ligand sets are coordinately bound to the metal ions to which the bioactive substance is not coordinately bound.

Imaging of Enzyme Activity

This invention relates to biochemistry and magnetic resonance imaging.

Ultra-high specificity fluorescent labeling

A self-assembled relay probe for detecting a target material is provided including: a first peptide tag bound to the target material; and a first fluorescent conjugate including a first fluorochrome and a first tag binding group; wherein the first fluorescent conjugate selectively associates with the first tag. The probe further includes a second peptide tag bound to the target material; and a second fluorescent conjugate including a second fluorochrome having a longer wavelength and distinct excitation and emission maxima from the first fluorochrome and a second tag binding group. Upon exposure to the target material, the first and second fluorescent conjugates independently associate with the first and second peptide tags, respectively, so as to be a distance apart represented by about 0.1 times R0 to about 2 times R0, such that upon excitation of the first fluorescent conjugate, fluorescence resonance energy transfer results in excitation of the second fluorescent conjugate, yielding detectable emission from the second fluorescent conjugate.

Open channel solid phase extraction systems and methods

The invention provides, inter alia, methods of extracting an analyte from a solution comprising the steps of: passing a solution containing an analyte through an extraction channel having a solid phase extraction surface, whereby analyte adsorbs to the extraction surface of said extraction channel; and eluting the analyte by passing a small volume of desorption solvent through the channel. The invention also provides, inter alia, methods of extracting an analyte from a solution comprising the steps of: passing a solution containing an analyte through an extraction channel having a solid phase extraction surface, whereby analyte adsorbs to the extraction surface of said extraction channel; eluting the analyte by passing a desorption solvent through the channel; and collecting the eluted analyte, wherein a small volume of eluant is collected.

Coloring agent comprising transition metals

The present invention relates to a composition for coloring keratin fibers and a method of using the same. The composition of the present invention contains at least one dye precursor, and one or more clathrate compounds that contain transition metal complexes.

Iron chelate solutions

A method for the preparation of an aqueous solution of iron polyprotic acid chelate complexes, comprising reacting a solution of a mixture of a first polyprotic acid or a salt thereof, said first acid being capable of chelating iron, and a second polyprotic acid or a salt thereof, said second acid being capable of chelating iron and being different from the first acid, with iron in the presence of an oxidizing agent, with the proviso that at least part of the carboxylic acid groups in the first and second acids is present in salt form and at least part of the carboxylic acid groups in the first and second acids is present in acid form. Preferably, the first and second polyprotic acids may be selected from ethylenediaminetetraacetic acid (EDTA), N-hydroxyethyl-ethylenediaminetriacetic acid (HEDTA), and diethylenetriaminepentaacetic acid (DTPA), and the iron is selected from Fe-powder, Fe(OH)2 and FeCO3. Part of the polyprotic acid groups in the first and second acids is present in the salt form, the salt being selected from ammonium and alkali metal ions, in particular K , Na and mixtures thereof. The method makes it possible to obtain aqueous solutions containing high contents of iron, such as up to approximately 7% by weight of iron, for use as a plant nutrient, mainly in soil-free plant culturing.

The Ion-exchange Chromatography of Imino Derivatives of Glycine

The resolution of the six imino derivatives of glycine (Gly) by ion-exchange chromatography is described.The imino compounds included iminodiacetonitrile (1), iminodiacetamide (2), iminodiacetic acid (3), α-(cyanomethylamino)acetamide (4), α-(cyanomethylamino)acetic acid (5), and α-(carbamoylmethylamino)acetic acid (6).A mixture of 1-6 was chromatographed along with Gly, glycinamide, aminoacetonitrile, and NH3 with an automatic amino acid analyzer using Aminex A-4 resin column (0.25φ x 50 cm) and sodium citrate buffers.When the initial buffer of pH 3.25 was changed to pH 6.50 15 min after beginning the analysis, these ten components were completely resolved.The analysis was completed in about 4.5 h.The stability of 1, 4, and 5 in aqueous media at room temperature was also studied.

Process for preparing nitrilotriacetonitrile

The preparation of methylene-bis-iminodiacetonitrile and nitrilotriacetonitrile by the reaction of formaldehyde, ammonia and hydrogen cyanide under acidic conditions involving a particular procedure of adding hydrogen cyanide to an acidified liquid phase adduct of ammonia and formaldehyde; the preparation of nitrilotriacetonitrile from methylene-bis-iminodiacetonitrile; and the preparation of nitrilotriacetic acid from methylene-bis-iminodiacetonitrile by carboxymethylation under alkaline conditions. Nitrilotriacetonitrile is particularly useful in the formation, by hydrolysis, of nitrilotriacetic acid of particular value as a chelating or complexing agent.