84194-64-9

Basic information

• Product Name: (R)-(+)-1-Phenyl-1-butyl acetate
• Synonyms: (R)-(+)-1-Phenyl-1-butyl acetate
• CAS NO: 84194-64-9
• Molecular Weight: 192.258
• Mol File: 84194-64-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: (R)-(+)-1-Phenyl-1-butyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-1-Phenyl-1-butyl acetate(84194-64-9)
• EPA Substance Registry System: (R)-(+)-1-Phenyl-1-butyl acetate(84194-64-9)

Safety Data

• Hazardous Substances Data: 84194-64-9(Hazardous Substances Data)

Upstream product

• 22135-49-5 (S)-1-phenylbutan-1-ol 
• 108-24-7 acetic anhydride 
• 108-05-4 vinyl acetate 
• 614-14-2 1-Phenyl-1-butanol 
• 86561-24-2 (RS)-1-phenyl-1-butanol acetate 
• 495-40-9 propiophenone 
• 22144-60-1 (R)-1-butylphenylethanol 
• 100-42-5 styrene 
• 127-09-3 sodium acetate 
• 75-03-6 ethyl iodide 

Downstream Products

• 22144-60-1 (R)-1-butylphenylethanol 

Relevant articles and documents

Rh-catalyzed asymmetric hydrogenation of α-aryl-β-alkylvinyl esters with chiral ferrocenylphosphine-phosphoramidite ligand

An enantioselective Rh-catalyzed hydrogenation of E/Z mixtures of trisubstituted vinyl esters has been disclosed. With a combination of [Rh(COD)2]BF4 and a structurally fine-tuning chiral ferrocenylphosphine-phosphoramidite ligand as the catalyst, a variety of E/Z mixtures of α-aryl-β-alkylvinyl esters have been successfully hydrogenated in high yields and with good to high enantioselectivities (up to 96% ee). The presence of a small amount of tBuOH proved to be beneficial to improve the hydrogenation outcome.

Acetate compound synthesis method

The invention provides an acetate compound synthesis method, and belongs to the field of organic synthesis, wherein the synthesis method has advantages of simple reaction system, no requirement of additional metal catalysts, no requirement of heating, high reaction and efficient synthesis of acetate compounds. According to the technical scheme, the preparation method comprises: respectively addinga styrene compound, an iodoalkyl compound and sodium acetate into a reactor, and carrying out an irradiation reaction for 2-10 h at a room temperature of 20-25 DEG C under a 10 W white daylight lampunder the actions of DDQ and ethanol; and after the reaction is finished, carrying out column chromatography separation to obtain the acetate compound. The method of the invention can be used in synthesis experiments of acetate compounds.

Substrate specificity of an esterase from the archaeon Sulfolobus tokodaii bearing a GGG(A)X motif

A GGG(A)X-type esterase (Est0071) from an archaeon catalyzes asymmetric hydrolysis of prochiral bulky malonic diesters in good enantioselectivity. The selectivity of Est0071 was for the opposite enantiomer to that previously shown for pig liver esterase, and the resulting enantiomeric excess of the products was higher. Est0071 could also catalyze the hydrolysis of various acetates of secondary alcohols, and showed moderate enantioselectivity in these reactions.