856899-98-4

Basic information

• Product Name: methyl 2-dihydroxy-3-(4-methoxyphenyl)propanoate
• Synonyms: methyl 2-dihydroxy-3-(4-methoxyphenyl)propanoate
• CAS NO: 856899-98-4
• Molecular Weight: 210.23
• Mol File: 856899-98-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: methyl 2-dihydroxy-3-(4-methoxyphenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-dihydroxy-3-(4-methoxyphenyl)propanoate(856899-98-4)
• EPA Substance Registry System: methyl 2-dihydroxy-3-(4-methoxyphenyl)propanoate(856899-98-4)

Safety Data

• Hazardous Substances Data: 856899-98-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 98081-75-5 2-azido-3-(4-methoxyphenyl)acrylic acid methyl ester 
• 122517-80-0 (2S,3R)-(-)-methyl 2,3-dihydroxy-3-(p-methoxyphenyl)propionate 
• 58236-76-3 3-chloro-4-methoxy cinnamic acid 
• 832-01-9 methyl p-methoxycinnamate 
• 830-09-1 3-(4'-methoxyphenyl)propenoic acid 
• 1415012-36-0 methyl 2,3-dihydroxy3-(3-chloro-4-methoxyphenyl)propanoate 
• 123-11-5 4-methoxy-benzaldehyde 
• 137173-40-1 (2S,3R)-methyl p-methoxycinnamate epoxide 
• 856899-97-3 2-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-phenyl)-propionic acid methyl ester 

Downstream Products

• 856899-99-5 (S)-3-(4-Methoxy-phenyl)-2-(toluene-4-sulfonyloxy)-propionic acid methyl ester 
• 23508-35-2 (S)-2-hydroxy-3-(4-hydroxy-phenyl)-propionic acid 
• 875112-26-8 methyl (S)-2-methoxy-3-(4-methoxyphenyl)propionate 
• 945292-58-0 (S)-2-Hydroxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-propionic acid 
• 856900-00-0 Toluene-4-sulfonic acid (S)-1-hydroxymethyl-2-(4-methoxy-phenyl)-ethyl ester 
• 1415012-34-8 methyl 2-azido-3-(4-methoxyphenyl)propanoate 
• 94790-24-6 (2R)-tert-butoxycarbonylamino-3-(4-methoxyphenyl)propionic acid methyl ester 

Relevant articles and documents

Asymmetric transfer hydrogenation of α-azido acrylates

The asymmetric transfer hydrogenation of α-azido acrylates has been explored, a range of α-hydroxy esters are produced with good enantioselectivities (80-90% ee). The reaction was conducted in the wet HCO2H/NEt3 with Ru-TsDPEN A.

Synthesis of unit-B of cryptophycin-24 via Sharpless asymmetric dihydroxylation

A synthetic pathway for the synthesis of unit-B of cryptophycin-24 has been developed using Sharpless asymmetric dihydroxylation as the key step. This study shows that direct azidation of α-hydroxy acid ester using diphenylphosphoryl azide is beneficial to asymmetric synthesis of α-amino acid without the loss of chirality during the transformation.

Unusual migrations and cyclization in the preparation of β-azido alcohols from β-hydroxy esters

Migration of TBDMS and Boc groups from 2° alcohols to 1° alcohols during the reduction of β-hydroxy esters has been observed. Also, unusual cyclization has been noticed during tosylation of benzylic alcohol in tert-butyl ((2R)-2-hydroxy-2-phenyl ethyl)car