85814-98-8

Upstream product

• 67-56-1 methanol 
• 124-41-4 sodium methylate 
• 1191263-83-8 4-chloro-6-phenyl-pyridine-1-carboxylic acid ethyl ester 
• 7500-03-0 2-Methyl-6-phenyl-1,4-dihydropyridin-4-on 
• 412923-41-2 4-chloro-2-methyl-6-phenyl-pyridine 
• 26567-78-2 (Z)-4-(phenylamino)-3-penten-2-one 
• 123-54-6 acetylacetone 
• 85814-95-5 methyl 4-chloro-6-phenylpyridine-2-carboxylate 
• 85814-93-3 4-hydroxy-6-phenylpyridine-2-carboxamide 
• 78296-37-4 4-hydroxy-6-phenylpyridine-2-carboxylic acid 
• 2397-77-5 Ethyl 4-oxo-6-phenyl-4H-pyran-2-carboxylate 
• 85814-97-7 methyl 4-methoxy-6-phenylpyridine-2-carboxylate 

Downstream Products

• 78296-45-4 4-Methoxy-6-phenyl-pyridine-2-carboxylic acid (1H-tetrazol-5-yl)-amide 

Relevant academic research and scientific papers

SUBSTITUTED 2-PHENYL-PYRIDINE DERIVATIVES

The present invention relates to compounds of formula I wherein R1, R2, R4, R5, Ra, Rb, n, W and Z are as defined in the application, their preparation and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.

SUBSTITUTED 2-PHENYL-PYRIDINE DERIVATIVES

The present invention relates to compounds of formula (I) wherein R1, R2, R4, R5, Ra, Rb, n, W and Z are as defined in the application, their preparation and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.