861721-49-5

Basic information

• Product Name: (E)-1,1-difluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol
• Synonyms: (E)-1,1-difluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol
• CAS NO: 861721-49-5
• Molecular Weight: 324.348
• Mol File: 861721-49-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (E)-1,1-difluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1,1-difluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol(861721-49-5)
• EPA Substance Registry System: (E)-1,1-difluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol(861721-49-5)

Safety Data

• Hazardous Substances Data: 861721-49-5(Hazardous Substances Data)

Upstream product

• 1535-65-5 difluoromethyl phenyl sulfone 
• 104-55-2 3-phenyl-propenal 
• 14371-10-9 (E)-3-phenylpropenal 
• 115262-01-6 [bromo(difluoro)methyl]-trimethyl-silane 
• 873-55-2 sodium benzenesulfonate 
• 101068-11-5 ethyl 2,2-difluoro-2-(phenylthio)acetate 
• 130409-81-3 ethyl (2,2-difluoro-2-phenylsulfinyl)acetate 
• 78031-08-0 [(bromodifluoromethyl)sulfanyl]benzene 
• 108-98-5 thiophenol 
• 80351-58-2 [(bromodifluoromethyl)sulfonyl]benzene 
• 536975-50-5 [difluoro(phenylsulfonyl)methyl](trimethyl)silane 

Downstream Products

• 153801-13-9 (E)-1,1-difluoro-4-phenylbut-3-en-2-ol 

Relevant articles and documents

Efficient nucleophilic difluoromethylation of aldehydes with (phenylsulfonyl)difluoromethylzinc and (phenylsulfonyl)difluoromethylcadmium reagents

A new strategy for nucleophilic addition to aldehydes with difluoromethyl organometallic reagents has been developed by functionalizing the difluoromethyl moiety with the phenylsulfonyl group (SO2Ph). This electron-withdrawing group influences

Decarboxylative difluoromethylation of aldehydes with PhSO2CF2COOK: A facile and efficient access to difluoromethylated carbinols

A novel decarboxylative difluoromethylation reaction of PhSO2CF2COOK with aldehydes under metal- and ligand-free conditions has been developed. The reaction is very mild and tolerates a wide range of aldehydes (both enolizable and non-enolizable aldehydes), providing a facile and efficient method for the synthesis of structurally diverse difluoromethylated carbinols in moderate to excellent yields.

Preparation of 1-aryl-2,2-difluoro enol esters via dehydrosulfonylation of α-(phenylsulfonyl)difluoromethylated benzoates

1-Aryl-2,2-difluoro enol benzoates 4 has been prepared from α-(phenylsulfonyl)-difluoromethylated benzoates 3, which can be readily obtained from the reactions between simple aldehydes and PhSO2CF2H (or TMSCF2SO2/sub