874-59-9Relevant articles and documents
Synthesis and Anti-Oomycete Activity of 1-Sulfonyloxy/Acyloxydihydroeugenol Derivatives
Chen, Genqiang,Zhu, Lina,He, Jiaxuan,Zhang, Song,Li, Yuanhao,Guo, Xiaolong,Sun, Di,Tian, Yuee,Liu, Shengming,Huang, Xiaobo,Che, Zhiping
, (2021/08/07)
Endeavor to discover biorational natural products-based fungicides, two series (26) of novel 1-sulfonyloxy/acyloxydihydroeugenol derivatives (3a–p and 5a–j) were prepared and assessed for their fungicidal activity against P. capsici Leonian, in vitro. Res
Convenient metal-free direct oxidative amidation of aldehyde using dibromoisocyanuric acid under mild conditions
Kang, Soosung,La, Minh Thanh,Kim, Hee-Kwon
supporting information, p. 3541 - 3546 (2018/08/29)
A facile method for the direct synthesis of amides from aldehydes is described. Amide bonds were synthesized by an oxidative amidation in the presence of dibromoisocyanuric acid (DBI). Treatment of aromatic and aliphatic aldehydes with dibromoisocyanuric acid generated acyl bromide intermediates, which were employed to react with a variety of secondary and primary amines to give amides. Through this reaction method, various amides were synthesized directly from aldehydes under mild conditions in high yields and short times. This facile and efficient procedure provides potential strategy for the direct synthesis of amides from aldehydes.
Nucleophilic Substitution at a Trigonal Carbon. Part 5. Substituent Effects in the Reactions of Aromatic Acyl Bromides with Methanol in Acetonitrile
Kevill, Dennis N.,Knauss, Donald C.
, p. 307 - 312 (2007/10/02)
The kinetics of the methanolysis of benzoyl bromide and eight para- or meta-substituted derivatives in acetonitrile at 25.0 deg C can be analysed in terms of the simultaneous operation of overall second- and third-order processes.In turn, each of these processes can be analysed in terms of the simultaneous operation of two reaction channels, which are proposed to involve a carbonyl addition-elimination mechanism (favoured for electron-withdrawing substituents) and a process (SN2-SN1) proceeding through a loose SN2-type transition state.For the p-methoxybenzoyl bromide substrate, a third reaction channel is observed, but only for the overall second-order process (first-order in methanol), and this is tentatively described as involving electrophilic assistance by a methanol molecule to an ionization (SN1) pathway.