882866-41-3

Upstream product

• 14802-18-7 2-phenyl-1H-quinolin-4-one 
• 551-93-9 2-aminoacetophenone 
• 98-88-4 benzoyl chloride 
• 6011-26-3 2'-acetylbenzanilide 
• 55-21-0 benzamide 
• 2142-69-0 2-bromophenyl methyl ketone 
• 536-74-3 phenylacetylene 
• 119-61-9 benzophenone 
• 615-43-0 2-iodophenylamine 
• 1027223-93-3 N-(2-iodophenyl)-1,1-diphenylmethanimine 
• 132960-13-5 N-methoxy-N-methyl-3-phenyl-2-propynamide 
• 1027223-95-5 methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate 

Downstream Products

• 14802-18-7 2-phenyl-1H-quinolin-4-one 
• 61707-51-5 3-benzoyl-2-phenyl-quinolin-4-(1H)-one 
• 1079284-12-0 4-chloro-3-iodo-2-phenylquinoline 
• 882866-45-7 3-iodo-1-methyl-2-phenylquinolin-4(1H)-one 

Relevant academic research and scientific papers

Mild, rapid and efficient metal-free synthesis of 2-aryl-4-aryloxyquinolines via direct Csp2[sbnd]O bond formation by using diaryliodonium salts

An efficient ligand- and transition metal-free procedure for the direct Csp2[sbnd]O bond formation for the arylation of 2-aryl-4-quinolones was developed. The synthesis of the starting quinolones was carried out under our optimized C

Generation of ArS- and ArSe-Substituted 4-Quinolone Derivatives Using Sodium Iodide As an Inducer

An operationally simple sodium iodide-mediated C-S and C-Se bond formation protocol involving substituted 4-quinolone and thiols/diselenide to generate different ArS/ArSe-substituted 4-quinolone derivatives in excellent yields was developed. The versatili

Photoredox halogenation of quinolones: The dual role of halo-fluorescein dyes

An efficient C-3 halogenation of quinolin-4-ones is reported with halogenated fluorescein dyes which serve both as a halogen source and photocatalyst. This reaction shows broad substrate scope and gives good to excellent yields of C-3 brominated/iodinated

Pd-NHC catalysed Carbonylative Suzuki coupling reaction and its application towards the synthesis of biologically active 3-aroylquinolin-4 (1H)-one and acridone scaffolds

We have unfolded a convenient and mild protocol for the synthesis of diaryl ketones via Pd- NHC catalysed carbonylative Suzuki coupling reaction. Notably, this method offers advantages like no use of toxic CO gas, shorter reaction time, high yield, and broad substrate scope. Several sensitive functional groups (like-COMe, -COOMe, -F, -Cl, -Br, -NH2, -CN) are well tolerated in this reaction. In addition, we have also demonstrated a new efficient route for the synthesis of biologically active and pharmaceutically important 2-substituted 3-Aroylquinolin-4(1H)-ones and acridone scaffolds.

Synthesis and cyclisation studies of (E)-2-aryl-1-methyl-3-styrylquinolin-4(1H)-ones

The synthesis of (E)-2-aryl-1-methyl-3-styrylquinolin-4(1H)-ones, through the Heck reaction of 2-aryl-3-iodo-1-methyl-quinolin-4(1H)-ones with styrene is described. 2-Aryl-3-iodo-1-methyl-2-quinolin-4(1H)-ones can be obtained efficiently in a two-step tra

Scaffold-divergent synthesis of ring-fused indoles, quinolines, and quinolones via iodonium-induced reaction cascades

N-(2-Iodophenyl)imines A are readily formed from Schiff's base condensation of 2-iodoanilines with carbonyls and ketals. These imines provide useful substrates in scaffold-divergent synthesis through the attachment of an alkyne (Songashira coupling or acyl substitution of a Weinreb amide) followed by an iodonium-induced reaction cascade to give ring-fused indoles B, quinolines C, or quinolones D depending on the reaction conditions employed.

Synthesis and further studies of chemical transformation of the 2-aryl-3-halogenoquinolin-4(1H)-one derivatives

The C-3 brominated and iodinated derivatives were prepared from the corresponding 2-arylquinolin-4(1H)-ones and their NMe-4-oxo derivatives using pyridinium tribromide in acetic acid or iodine-Na2CO3 mixture in THF. The results of fu

One-pot synthesis of 2-substituted furo[3,2-c]quinolines via tandem coupling-cyclization under Pd/C-copper catalysis

Pd/C-Cu catalyzed coupling reactions of 3-iodo-1H-quinolin-4-ones with a variety of terminal alkynes afforded furo[3,2-c]quinolines regioselectively in good to excellent yields. 3-Alkynyl quinolones were isolated under the same reaction conditions when th