90843-22-4

Basic information

• Product Name: 2-(prop-1-en-1-yl)benzoic acid
• Synonyms: 2-(prop-1-en-1-yl)benzoic acid
• CAS NO: 90843-22-4
• Molecular Weight: 162.188
• Mol File: 90843-22-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-(prop-1-en-1-yl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(prop-1-en-1-yl)benzoic acid(90843-22-4)
• EPA Substance Registry System: 2-(prop-1-en-1-yl)benzoic acid(90843-22-4)

Safety Data

• Hazardous Substances Data: 90843-22-4(Hazardous Substances Data)

Upstream product

• 34599-72-9 methyl 2-(prop-1-en-1-yl)benzoate 
• 16859-59-9 3-hydroxy-1(3H)-isobenzofuranone 
• 1530-32-1 ethyltriphenylphosphonium bromide 
• 75-07-0 acetaldehyde 
• 119-67-5 o-carboxybenzaldehyde 
• 4122-56-9 methyl o-formylbenzoate 
• 17475-41-1 3-ethylphthalide 
• 127-08-2 potassium acetate 
• 93-55-0 1-phenyl-propan-1-one 
• 103441-58-3 1-(2-iodophenyl)propan-1-one 
• 144-62-7 oxalic acid 
• 88-65-3 2-bromobenzoic-acid 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 124-38-9 carbon dioxide 

Downstream Products

• 1351766-10-3 2-p-tolyl-3-vinylisoindolin-1-one 
• 1351766-13-6 2-(3,4-dimethylphenyl)-3-vinylisoindolin-1-one 
• 1351766-15-8 2-(3,4-dimethylphenyl)-3-methylisoquinolin-1(2H)-one 
• 1351766-17-0 2-(2,4-dimethylphenyl)-3-vinylisoindolin-1-one 
• 1351766-19-2 2-(2,4-dimethylphenyl)-3-methylisoquinolin-1(2H)-one 
• 1351766-21-6 2-(4-chlorophenyl)-3-vinylisoindolin-1-one 
• 1351766-23-8 2-(4-chlorophenyl)-3-methylisoquinolin-1(2H)-one 
• 32346-23-9 (Z)-3-ethylidene-2-phenylisoindolin-1-one 
• 32346-24-0 (E)-3-ethylidene-2-phenylisoindolin-1-one 
• 1351765-45-1 (E)-N-phenyl-2-(prop-1-enyl)benzamide 
• 1351765-58-6 (E)-2-(prop-1-enyl)-N-p-tolylbenzamide 
• 1351765-60-0 (E)-N-(3,4-dimethylphenyl)-2-(prop-1-enyl)benzamide 
• 1351765-62-2 (E)-N-(2,4-dimethylphenyl)-2-(prop-1-enyl)benzamide 
• 1351765-64-4 (E)-N-(4-chlorophenyl)-2-(prop-1-enyl)benzamide 

Relevant articles and documents

Palladium-catalyzed: Ortho -halogen-induced deoxygenative approach of alkyl aryl ketones to 2-vinylbenzoic acids

The 2-vinylbenzoic acids have wide applications in the field of polymer chemistry and are key precursors for the synthesis of important bioactive molecules. Herein, an ortho-halogen-induced deoxygenative approach for the generation of 2-vinylbenzoic acids from alkyl aryl ketones by palladium catalysis is discovered and explored. This approach requires no base or stoichiometric additives and can be carried out through a simple one-step process. Furthermore, the present reaction is scalable up to one-gram scale. The commercially available palladium on carbon (5 wt%) was used as a heterogeneous catalyst and showed excellent recyclability (5 times) without significant loss in catalytic activity. Pleasingly, under our optimized conditions, the alpha alkyl substituted 2-iodoacetophenones exhibit good diastereoselectivity and predominantly (E)-2-vinylbenzoic acids were obtained with good to excellent yields.

Copper-Catalyzed Amino Lactonization and Amino Oxygenation of Alkenes Using O-Benzoylhydroxylamines

A copper-catalyzed amino lactonization of unsaturated carboxylic acids has been achieved as well as the analogous intermolecular three-component amino oxygenation of olefins. The transformation features mild conditions and a remarkably broad substrate sco

C3-symmetric cinchonine-squaramide-catalyzed asymmetric chlorolactonization of styrene-type carboxylic acids with 1,3-dichloro-5,5- dimethylhydantoin: An efficient method to chiral isochroman-1-ones

A more practical and efficient catalytic asymmetric chlorolactonization of styrene-type carboxylic acids with 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) using C3-symmetric cinchonine-squaramide (CSCS) as organocatalyst has been developed. A series of chiral chloro-substituted isochroman-1-ones was obtained in excellent yields (up to 95%) and enantioselectivities (up to 99% ee), whwereby the results for chloro-substituted isochroman-1-ones are the best ever achieved. The catalyst can be recovered and reused for six cycles. Moreover, the chlorolactonization product 3b was further transformed to optically active bicyclic isochroman-1-one derivatives in high yield without losing the enantioselectivity. Furthermore, compounds 3e and 2n proved to be highly potent inhibitors of the HIV-1 in TZM-bl cells.