92166-40-0Relevant academic research and scientific papers
Design, synthesis, crystal structure, in vitro cytotoxicity evaluation, density functional theory calculations and docking studies of 2-(benzamido) benzohydrazide derivatives as potent AChE and BChE inhibitors
Altaf, Ataf Ali,Arshad, Muhammad Nadeem,Asiri, Abdullah M.,El-Bahy, Salah M.,Elnaggar, Ashraf Y.,Kausar, Naghmana,Kausar, Samia,Murtaza, Shahzad,Tatheer, Adina,Zaib Saleem, Rahman Shah
, p. 154 - 167 (2022/01/19)
A series of hydrazone derivatives of 2-(benzamido) benzohydrazide was designed, synthesized, and characterized utilizing FTIR, NMR and UV spectroscopic techniques along with mass spectrometry. Compound 10 was also characterized through X-ray crystallograp
A highly selective diarylethene fluorescence sensor of aluminum ion and its application
Fan, Congbin,Liu, Gang,Pu, Shouzhi,Wang, Huaxin,Zhao, Heng
, (2020/10/18)
A novel diarylethene derivative 1O with the unit of N-(2-(hydrazinecarbonyl)phenyl)benzamide was designed and synthesized successfully. The sensor showed excellent photochromism and specific fluorescent detection toward aluminum ion with rarely interfering. The emission intensity could increase nearly by 100 folds with aluminum ion and the color changed from dark to Aqua green. The low limit of detection (LOD) of 1O was determined as 3.26 × 10-8 mol L-1. Additionally, the sensor could be used in logic circuit and aluminum ion detection in untreated water.
Aluminum ion detection fluorescent probe based on bifunctional organic small molecule as matrix and preparation method and application thereof
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Paragraph 0095-0099, (2021/11/14)
The invention discloses an aluminum ion detection fluorescent probe based on a bifunctional organic small molecule as a matrix and a preparation method and application of the fluorescence probe, and the structural formula is shown I. To the invention, 1, 8 - naphthalimide and isoquinoline hydrazide or 2 - benzamide benzoyl hydrazine are used as fluorescent groups, and the prepared Schiff base type probe NIQ or NBP is prepared into a solution Al through condensation reaction. 3 + High sensitivity and high selectivity are exhibited, and at the same time, the structure is stable. The low toxicity and cell infiltration capability is strong, and the trace metal aluminum ions in the living Hela cells are successfully detected. The preparation method of the fluorescent probe is simple, the raw materials are easily available, the obtained product is solid powder, is easy to store, and has a high application development prospect.
Synthesis, characterization, biological evaluation and molecular docking studies of N-functionalized derivatives of 2-aminobenzohydrazide
Arshad, Muhammad Nadeem,Ashraf, Zaman,Asim, Mulazim Hussain,Asiri, Abdullah M.,Javid, Noman,Kausar, Naghmana,Murtaza, Shahzad,Rashid, Robina
, (2020/03/19)
In this paper, N-functionalized derivatives of methyl anthranilate (1–3) were prepared by reacting it with various acid chlorides to give amide derivatives (1–3) which were further converted to benzohydrazide derivatives (4–6) by reacting them with hydraz
A new series of Schiff base derivatives bearing 1,2,3-triazole: Design, synthesis, molecular docking, and α-glucosidase inhibition
Nasli-Esfahani, Ensieh,Mohammadi-Khanaposhtani, Maryam,Rezaei, Sepideh,Sarrafi, Yaghoub,Sharafi, Zeinab,Samadi, Nasser,Faramarzi, Mohammad Ali,Bandarian, Fatemeh,Hamedifar, Haleh,Larijani, Bagher,Hajimiri, Mirhamed,Mahdavi, Mohammad
, (2019/08/12)
A series of new Schiff bases bearing 1,2,3-triazole 12a?o was designed, synthesized, and evaluated as α-glucosidase inhibitors. All the synthesized compounds showed promising inhibition against α-glucosidase and were more potent than the standard drug aca
Synthesis, structural characterization and biological evaluation of mononuclear transition metal complexes of zwitterionic dehydroacetic acid N-aroylhydrazone ligand
Kendur, Umashri,Chimmalagi, Geeta H.,Patil, Sunil M.,Gudasi, Kalagouda B.,Frampton, Christopher S.
, (2018/02/21)
Synthesis and characterization of mononuclear transition metal complexes viz., Co(II), Ni(II), Cu(II) and Zn(II) with a newly designed ligand, (E)-2-benzamido-N'-(1-(2-hydroxy-6-methyl-4-oxo-4H-pyran-3-yl) ethylidene) benzohydrazide (H2L) are r
Synthetic studies and antibacterial activity of nucleobases and their N- and S-glucosides from 2-amino benzoic acid and its benzamido derivatives
Benhammadi, Samia,Iraten, Salima,Othman, Adil A.
, p. 2567 - 2576 (2016/11/22)
A series of S-glucosides 11a-14a and their benzamido derivatives 11b-14b have been synthesized by reacting D-glucose with thiol groups of 5-(2′-aminophenylene)-1,3,4-oxadiazole-2-thioles 7(a,b), 5-(2′-aminophenylene)-1,3,4-thiadiazole-2-thiols 8(a,b), 5-(2′-aminophenylene)-1,2,4-triazole-3-thiols 9(a,b) and 5-(2′-aminophenylene)-4-N-amino-1,2,4-triazole-3-thiols 10(a,b). The thiols 7(a,b)-10(a,b) have been synthesized from hydrazides 3(a,b) which already been synthesized from 2-aminobenzoic acid and its benzamido derivative. All synthesized compounds were characterized by IR, UV,1H- and13C- NMR. Nucleobases and a representative of S-glycoside were tested in vitro against the following microorganisms: two Gram-positive bacteria Staphylococcus aureus and Bacillus cereusand two Gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa and they exhibited significant effects. Amykacine was used as positive standard.
2-Phenyl-3-(2-aminobenzamido)quinazolin-4(3H)-one as a synthon for bisazaheterocvclics
Reddy, G. Mahesh,Reddy, P. S. N.
, p. 166 - 168 (2007/10/03)
Synthesis of 2-phenyl-3-(2-aminobenzamido)quinazolin-4(3H)-one 7, a synthon of unsymmetrical bisazaheterocyclics, is reported from 3-amino-2-phenylquinazolin-4(3H)-one 2. In an alternate synthetic route 7 has been prepared by refluxing 2-aminobenzoylhydrazine and 2-phenyl-3,1-benzoxazin-4(H)-one 1 in pyridine.
Modified Procedure for the Preparation of 5-Nitro-2-furylmethylene Diacetate and Its Use in the Synthesis of Some Novel (5-Nitro-2-furyl)azomethines via 5-Nitro-2-furaldehyde
Vlaovic, Djordje,Milic, Bozidar Lj.,Mackenzie, Kenneth
, p. 1201 - 1218 (2007/10/02)
A modified two-step procedure for the preparation of 5-nitro-2-furylmethylene diacetate (3) by nitration of 2-furaldehyde (1) or 2-furylmethylene diacetate (4) with acetyl nitrate via 2-acetoxy-5-nitro-2,5-dihydro-2-furylmethylene diacetate (2), or 1,1,5-triacetoxy-2-hydroxy-5-nitro-3-penten (5) and 1,1,5-triacetoxy-2-hydroxy-5-nitro-2,4-pentadiene (6), has been developed.Acid hydrolysis of 3 yields 5-nitro-2-furaldehyde (7) which is used in the carbonylamine condensation with various hydrazines (9-11, 14, 17, 19, 21, 24, 25, 28, 29, 32, 34, 36, 38, 39, 41 and 44-54) prepared by known methods, in order to obtain some novel potentially pharmaceutically active (5-nitro-2-furyl)azomethines.
